Antimicrobial susceptibility of Moraxella catarrhalis isolated from children in Kalgoorlie–Boulder, Western Australia

Susceptibility of Clinical Moraxella catarrhalis Isolates in British Columbia to Six Empirically Prescribed Antibiotic Agents

“…As expected, all isolates showed susceptibility to amoxicillin/ clavulanate, clarithromycin and levofloxacin, which is consistent with the most current Canadian research (Table 3) and most international research (4,6,7,9–11). Complete sensitivity of all isolates to doxycycline and TMP/SMX was also observed, despite Canada-wide (2,12,13) (Table 3) and international studies (4,5,9,11) showing some resistance.…”

Antibiogram Pattern of <i>Moraxella catarrhalis</i> Isolates in Acute Exacerbation Chronic Obstructive Pulmonary Disease

“…This observation concurs with those of previous investigators who have stated that cigarette smoking and tobacco smoke exposure could exacerbate the COPD state [5,[8][9][10] . In line with others, we observed that 1 90% of M. catarrhalis isolates produced ␤ -lactamase [11,12] . Previous studies have found that nearly 100% of M. catarrhalis isolates are sensitive to a combination of penicillin and ␤ -lactamase inhibitors, fluoroquinolones, macrolides, tetracyclines and cotrimoxazole antibiotics [11,13] , and this was closely reflected in our study.…”

“…In line with others, we observed that 1 90% of M. catarrhalis isolates produced ␤ -lactamase [11,12] . Previous studies have found that nearly 100% of M. catarrhalis isolates are sensitive to a combination of penicillin and ␤ -lactamase inhibitors, fluoroquinolones, macrolides, tetracyclines and cotrimoxazole antibiotics [11,13] , and this was closely reflected in our study. In regards to erythromycin resistance, our study showed a rate of 32%, whereas an Australian study showed a rate of 4% and a Polish study documented 12% erythromycin resistance [14] .…”

Impact of recent antibiotics on nasopharyngeal carriage and lower airway infection in Indigenous Australian children with non-cystic fibrosis bronchiectasis

“…We did not test for azithromycin susceptibility as M. catarrhalis is almost universally susceptible to azithromycin. A recent Western Australian study, which included Indigenous children, reported that all 261 M. catarrhalis strains tested were susceptible to azithromycin [8]. In the current study, azithromycin susceptibility is the most likely explanation for M. catarrhalis lower airway infections being less prevalent in children who had received macrolides.…”