2011
DOI: 10.1128/aac.00979-10
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Antimicrobial Susceptibility ofBrucella melitensisIsolates in Peru

Abstract: Brucellosis is an important public health problem in Peru. We evaluated 48 human Brucella melitensis biotype 1 strains from Peru between 2000 and 2006. MICs of isolates to doxycycline, azithromycin, gentamicin, rifampin, ciprofloxacin, and trimethoprim-sulfamethoxazole were determined by the Etest method. All isolates were sensitive to tested drugs during the periods of testing. Relapses did not appear to be related to drug resistance.

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Cited by 45 publications
(37 citation statements)
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References 12 publications
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“…In contrast to the present study, other studies carried out in Peru (17) and China (18) reported no resistance to RIF. However, intermediate sensitivity to RIF was reported in some areas of Turkey (19,20) and in Malaysia (21).…”
Section: Discussioncontrasting
confidence: 54%
“…In contrast to the present study, other studies carried out in Peru (17) and China (18) reported no resistance to RIF. However, intermediate sensitivity to RIF was reported in some areas of Turkey (19,20) and in Malaysia (21).…”
Section: Discussioncontrasting
confidence: 54%
“…Unfortunately, we did not test streptomycin in the present work. The E-test method had previously been used by Maves et al (2011) with Brucella strains from Peru, and by Kasymbekov et al (2013) to investigate Brucella strains from Kyrgyzstan. Both of these prior reports showed that all isolates were sensitive to the tested antimicrobials.…”
Section: Resultsmentioning
confidence: 99%
“…Multidrug antimicrobial regimens are the mainstay of therapy because of high relapse rates reported with mono therapeutic approaches [40]. Medical therapy should be within the context of general medical supervision and, for severely ill patients, is best carried out in hospital if circumstances permit.…”
Section: Control and Prevention Of Human Brucellosismentioning
confidence: 99%