Antimicrobial Secondary Metabolites from the Marine-Derived Actinomycete Nocardiopsis synnemataformans HT06

Marine natural products

“…8 Continuing work on Gephyromycinifex aptenodytis derived from the gut microbiota of the Antarctic emperor penguin, Aptenodytes forsteri yielded an additional new angucyclinone analogue, 2-hydroxy-frigocyclinone 20 . 9 An aromatic glycoside 21 was identified from a sediment-derived collection of Nocardiopsis synnemataformans 10 and four new fluvirucin-type macrolactams, fluvirucins B7–B10 22 – 25 were isolated from a sponge-derived rare actinomycete Nonomuraea sp. 11 …”

“…8 Continuing work on Gephyromycinifex aptenodytis derived from the gut microbiota of the Antarctic emperor penguin, Aptenodytes forsteri yielded an additional new angucyclinone analogue, 2-hydroxyfrigocyclinone 20. 9 An aromatic glycoside 21 was identied from a sediment-derived collection of Nocardiopsis synnemataformans 10 and four new uvirucin-type macrolactams, uvirucins B7-B10 22-25 were isolated from a sponge-derived rare actinomycete Nonomuraea sp. 11 Using metabolomic-guided microbial strain prioritisation and genome-mining strategies, a new 5-aminosalicylate containing siderophore, pseudonochelin 26 was isolated from a sponge-derived Pseudonocardia sp.…”