Antimicrobial Potential of Siddha Polyherbal Formulation Aavarai Kudineer

Rajalakshmi, K; Shanmugapriya, P; Gj, Christian; Gladys, Jeeva; Banumathi, V.; Geethalakshmi, S. N.

doi:10.22207/jpam.12.2.66

Cited by 4 publications

(3 citation statements)

References 20 publications

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“…There was significant cytotoxic activity in the concentrations of 20μl and 80μl (p>0.05). At all concentrations the brine shrimp count was within limits (>60%) On analysis of previous literature it was found that, in a study conducted by R. Ganesan et al, 2018, the cytotoxic activity against HepG2 cells increased with an increase in the concentration with an IC 50 of 331.883 10.931 mg/mL [57]. In a study conducted by Parkash et al, it was observed that when an acute toxicity study was performed, there was no mortality observed in the test animals after oral administration of 2 g/kg dose of methanol extract of Abies webbiana Lindl which suggested that the preparation was safe for use which was in concordance with the current study [54].…”

Section: Bar Graph With Error Bar Shows the Cytotoxic Activity Of Abi...mentioning

confidence: 68%

Abies webbiana Ethanolic Extract Based Mouthwash and Its Antimicrobial and Cytotoxic Effect

Timothy

Nandhini

Varghese

et al. 2021

JPRI

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Aim: The aim of this study was to evaluate the antimicrobial and cytotoxic effect of Abies webbiana ethanolic extract based preparation of mouthwash and to compare these effects between different concentrations. Background: Abies webbiana leaves have been used in traditional siddha and ayurveda systems of medicine for common ailments such as cough, loss of appetite, indigestion, mental disorders, rheumatism, bronchitis, pulmonary infection, asthma, antiseptic and decongestant. Abies webbiana commonly known as talispatra belongs to family Pinaceae. The plant is distributed throughout India, mostly in the Himalayan region from Kashmir to Assam states. Materials and Methods: The preparation of Abies webbiana extract was done and antimicrobial activity of Abies webbiana were tested with Streptococcus mutans, Candida albicans, Enterococcus faecalis, Staphylococcus aureus through agar well diffusion method. Each bacterial culture was spread on the Luria-Bertani agar plates. Dried extract of Abies webbiana, dissolved in autoclave distilled water to make 25mg/mL, 50mg/mL, 100mg/mL. Incubated for 24 hours at 37o C and diameter of zone of inhibition were recorded in millimeter and compared with standard amoxicillin. Cytotoxic activity of Abies webbiana was assessed using brine shrimp lethality assay. A total of 10 nauplii were added into the three replicates of each concentration of the prepared extract. After the period of 24 hours the remaining brine shrimp were counted. Results: The results of the study revealed that the the Abies webbiana formulation based mouthwash is having significantly higher antimicrobial activity than the antibiotic against S. aureus at all the tested concentrations whereas against E. faecalis the antimicrobial effect was significantly lower than the antibiotic. Against S. mutans, higher concentrations of the mouthwash had the antimicrobial effect comparable to that of the antibiotic. The antimicrobial effect against C. albicans was very less for all the tested concentrations of the mouthwash and the antibiotic. This mouthwash also possessed cytotoxic effects on nauplii which were within normal limits and it was found that the nauplii alive was directly proportional to the concentrations except in the concentration of 40μl. Conclusion: Within the limitations of the current study, ethanolic extract of Abies webbiana based preparation of mouthwash shows the antimicrobial activity almost comparable to amoxicillin. It was also revealed that it possesses less cytotoxic effect against brine shrimp which are within normal limits.

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Section: Bar Graph With Error Bar Shows the Cytotoxic Activity Of Abi...mentioning

confidence: 68%

Abies webbiana Ethanolic Extract Based Mouthwash and Its Antimicrobial and Cytotoxic Effect

Timothy

Nandhini

Varghese

et al. 2021

JPRI

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“… Cassia auriculata, Cassia fistula, Syzygium jambos, Olaxscandens, Saussurea lappa, Terminalia arjuna, Cyperus rotundus AaviraiKudineer In-vitro Antibacterial activity Bacillus species that causes infections in wounds. [ 59 ] 54. Azadirachta indica (Leaves), Acacia nilotica (Bark), Ocimum sanctum (Leaves), Annona squamosal (Leaves), Curcuma longa (Rhizome 7%), Ricinus communis (Seed oil), Beewax Herboheal In-vitro and in-vivo ( Caenorhabditis elegans as model) Antibacterial activity against wound infective S. aureus [ 60 ] …”

Section: Resultsmentioning

confidence: 99%

Preclinical evidence of polyherbal formulations on wound healing: A systematic review on research trends and perspectives

Dubey¹,

Dixit²

2023

Journal of Ayurveda and Integrative Medicine

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“…Useful in the treatment of diabetes and antimicrobial and fungalinfection. 38 Talapotaka churna: It is a poly-herbal preparation contains C. auriculata, Emblica officinalis, berberis aristata, and Curcuma longa. It is useful in reducing blood glucose level hence this churna is used to treat diabetes (Table 3).…”

Section: Ayurvedic Formulations and Preparationsmentioning

confidence: 99%

Review on ethnobotany, phytochemistry, and pharmacological properties of Cassia auriculata

Sn¹,

B²,

Sp³

et al. 2020

PPIJ

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The herbal medicines are selecting over modern medicine due to their efficacy, safety, and lesser side effects. Cassia auriculata extremely used in Ayurvedic medicine. C. auriculata is commonly known as tanner's cassia, and it belongs to the family Caesalpiniaceae. It is reported to contain many phytoconstituents such as alkaloids, terpenoids, phenols and tannins, sugar saponins, flavonoids, quinines, steroids, and proteins. The ethnobotanical survey revealed that the C. auriculata was used for the treatment of diabetes, joint pain and inflammation, muscle pain, illness, cold, venereal disease, hair cleanser, reduce body heat, abdominal pain, vomiting, diarrhoea, and toothache. C. auriculata have many pharmacological properties, such as anti-diabetic, anti-oxidant, hepatoprotective, anticancer, anti-inflammatory, anti-hyperlipidemic activities, and many more. The present review focused on its botanical characters, phytochemical constituents, ethnobotanical uses, and pharmacological properties of C. auriculata.

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Antimicrobial Potential of Siddha Polyherbal Formulation Aavarai Kudineer

Cited by 4 publications

References 20 publications

Abies webbiana Ethanolic Extract Based Mouthwash and Its Antimicrobial and Cytotoxic Effect

Abies webbiana Ethanolic Extract Based Mouthwash and Its Antimicrobial and Cytotoxic Effect

Preclinical evidence of polyherbal formulations on wound healing: A systematic review on research trends and perspectives

Review on ethnobotany, phytochemistry, and pharmacological properties of Cassia auriculata

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