Antimicrobial phenylpropanoids from Piper sarmentosum

The anti-inflammatory activity of dillapiole and some semisynthetic analogues

“…There is great interest in phenylpropanoids because of their potential biological properties, including psychotropic, antimicrobial, antioxidant and cytotoxic properties (Shulgin, 1966;Masuda et al, 1991;Atsumi et al, 2000;Lago et al, 2004Lago et al, , 2005. Piper hispidinervum C.…”

Effect of leaf essential oil from Piper solmsianum C.DC. in mice behaviour

“…It has been frequent the isolation and chemical characterisation of arylpropanoids (Parmar et al 1997) from crude extracts and essential oils of Piperaceae species (saf-role, myristicin, eugenol, dillapiol, apiol, asarone). Arylpropanoids and related compounds have shown interesting biological properties including psychotropic, antimicrobial, antioxidant and cytotoxic effects (Shulgin & Sargent 1967, Masuda et al 1991, Priyadarsini et al 1998, Atsumi et al 2000. Piper solmsianum C.DC.…”

A review of the literature and latest advances in research ofPiper sarmentosum

“…The chemical constituents identified in the plant are pellitorine (Likhitwitayawuid & Ruangrungsi, 1987;Thitima et al, 2004;Tuntiwachwuttikul et al, 2006;Hussain et al, 2010a), guineensine (Thitima et al, 2004;Tuntiwachwuttikul et al, 2006), brachystamide B (Thitima et al, 2004;Tuntiwachwuttikul et al, 2006), sarmentine (Likhitwitayawuid & Ruangrungsi, 1987;Thitima et al, 2004;Tuntiwachwuttikul et al, 2006;Hussain et al, 2010a), brachyamide B (Thitima et al, 2004), 1-piperettyl pyrrolidine (Thitima et al, 2004), 3,4,5-trimethoxycinnamoyl pyrrolidine (Thitima et al, 2004), sarmentosine (Likhitwitayawuid & Ruangrungsi, 1987;Thitima et al, 2004;Tuntiwachwuttikul et al, 2006;Hussain et al, 2010a), (+) asarinin (Thitima et al, 2004), sesamin (Thitima et al, 2004;Tuntiwachwuttikul et al, 2006), N-[9-(3,4-methylenedioxyphenyl)-2E,4E,8E-nonatrienoyl] pyrrolidine (Tuntiwachwuttikul et al, 2006), methyl piperate (Thitima et al, 2004), β-sitosterol (Likhitwitayawuid & Ruangrungsi, 1987;Thitima et al, 2004;Tuntiwachwuttikul et al, 2006;Niamsa & Chantrapromma, 1983), stigmasterol (Thitima et al, 2004), aromatic alkene (Tuntiwachwuttikul et al, 2006), 1-allyl-2-methoxy-4,5-metylenedioxybenzene (Tuntiwachwuttikul et al, 2006;Masuda et al, 1991), sarmentide C (Tuntiwachwuttikul et al, 2006), pyrrole amide (Tuntiwachwuttikul et al, ...…”

“…Extracts of the plant have shown antibacterial activity against Escherichia coli and Bacillus subtilis due to 1-allyl-2,6-dimethoxy-3,4-methylenedioxybenzene (Masuda et al, 1991). Zaidan et al (2005) prepared in 95% ethanol (yield 0.5%) have demonstrated antibacterial activity-in the presence of ultraviolet light exposure at 350 nm for 2 h-against S. aureus and B. subtilis (zones of inhibition ranging 8-12 mm), whereas such extracts have not shown activity against E. coli W, E. coli M and P. aeruginosa (Cheeptham & Towers, 2002).…”