Antimicrobial Isoflavonoids from Erythrina crista galli Infected with Phomopsis sp.

Abstract

The isoflavonoids coumestrol, genistein and daidzein have been isolated and identified by bioassay-guided fractionation from the acetone extract of Erythrina crista galli young twigs infected with Phomopsis sp. These compounds showed antimicrobial activity against Bacillus brevis (MIC values 16.3, 64.8 and 137.8 μm, respectively). This is the first time that coumestrol, besides lutein and n-nonacosane, are reported in this species.

Phytochemical and Antimicrobial Study on the Leaf Extract of Tapinanthus dodoneifolius (Van Teigh) Loranthaceae

“…Tannins are known to be antimicrobial agent that tends to inhibit the growth of microorganism by precipitating out the microbial protein and thus depriving them of development [21]. In the present study, tannins were detected in the methanol and n-butanol extract fraction of the extract.…”

Structures of New Erythrinan Alkaloids and Nitric Oxide Production Inhibitors from Erythrina crista-galli

“…Heteronuclear multiple bond connectivity (HMBC) correlations ( Furthermore, one methoxy group was attached to C-3 as deduced from the HMBC correlations of methoxy protons H-18 to C-3. These data suggested that compound 1 has a gross structure similar to that of erythraline (7). Ultimately, the molecular formula of 1 indicated the presence of one extra oxygen atom.…”

“…It is also commonly called "Corticeira" in Brazil, and its bark is used for rheumatism, hepatitis, sedation, and hypnogenesis. 1) Phytochemical studies on this plant showed the presence of Erythrinan alkaloids, [2][3][4] benzylisoquinoline alkaloids, 5) isoflavonoids, 6,7) and pterocarpans. 8,9) The study of biosynthesis of Erythrinan alkaloids in Erythrina crista-galli was reported.…”

Erythrina, a Potential Source of Chemicals from the Neotropics

“…Also several flavonoids (Chacha, et al 2005;Chukwujekwu, et al, 2011;Doughari, 2011), isoflavonoids (Sato, et al, 2006;Kamdem Waffo, et al, 2006;Redko, et al, 2007) and pterocarpanes (Rukachaisirikul, et al, 2007a; have been mentioned as antimicotic and antibacterial agents. For instance, an arylbenzofuran, erypoegin F and four isoflavonoids, erypoegins G-J were isolated from the roots of E. poeppigiana and their structure were elucidated by spectroscopic evidence (Tanaka, et al, 2003).…”