Phytochemical and Antimicrobial Study on the Leaf Extract of Tapinanthus dodoneifolius (Van Teigh) Loranthaceae

Abstract

Leaves of Tapinanthus dodoneifolius is used as traditional medicine for the treatment of menstrual pain, wound, gonorrhea, and control of diarrhea and dysentery which was extracted by cold maceration in methanol. The concentrated methanol extract was subsequently partitioned with petroleum ether, chloroform, ethylacetate and n-butanol. Agar well Diffusion method was used to determine the antimicrobial activities of the extracts against Staphylococcus aureaus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Klebsiela pneumonia, Salmmnella typhi, Streptococcus pyogenes, Candida krusei, Candida tropicalis, and Candida albican at different concentrations. Antimicrobial sensitivity test indicated that, the extract inhibited the growth of all microorganisms to varying degrees except Pseudomonas aeruginosa and Candida krusei respectively. The in vitro antimicrobial screening revealed that, the extracts exhibited diverse activities against different microbe’s concentrations ranging from 2.5mg/ml-5mg/ml. The plant extract was found to contain flavonoids, terpenoids, saponins, tannins and cardiac glycosides which may be responsible for its antimicrobial properties. The result justifies the traditional use of the plant leaf in the treatment of menstrual pain, sexual transmitted diseases, wounds and control of dysentery and diarrhea.

Skrining Fitokimia Ekstrak Daun Benalu Kopi (Scurrula Parasitica L.) Dataran Tinggi Gayo

“…S. parasitica merupakan famili dari Lorantaceae yaitu tumbuhan berbunga dan berkayu umumnya dikenal mistletoe (tumbuhan parasit) yang ditemukan tumbuh di Benua Afrika, Asia, Eropa, Australia, Amerika Selatan dan Selandia Baru [4] Skrining fitokimia merupakan tahapan awal dari suatu penelitian yang bertujuan untuk memberikan gambaran tentang golongan senyawa yang terkandung di dalam tanaman yang sedang diteliti atau disebut metabolit sekunder. Metabolit sekunder umumnya hanya dijumpai pada satu spesies atau satu kelompok spesies, berbeda dengan metabolit primer (asam amino, nukleotida, gula dan lipid) yang dijumpai hampir di semua kingdom tumbuhan [9].…”

Acute Antidepressant Activity Investigation of Selected African Medicinal Plants in Mice: A Preliminary Study

“…[48] - [50]. Reports indicate decoctions from T. dodoneifolius and its synonyms have efficacy in traditional management of malarial fever, hyperglycemia, raised blood pressure, dysentery, nervous disorders, abdominal colic, neoplasms, diarrhea, and gonorrhea [51]- [56], and their extracts have been associated with a wide spectrum of pharmacological activities including antimalarial, hypotensive, antineoplastic, anti-dyspeptic, and antimicrobial [53]- [57] effects. Aqueous T. dodoneifolius bark extract had exhibited significant anxiolytic and antidepressant activities in mice, [58] but the leaf extract of this plant has not been screened for its antidepressant activity, and this study aims to assess its acute antidepressant activity in mice.…”