Antimicrobial Efficacy of Triphala and Propolis-modified Glass Ionomer Cement: An In Vitro Study

Paulraj, Jessy; Nagar, Priya

doi:10.5005/jp-journals-10005-1806

Cited by 8 publications

(4 citation statements)

References 34 publications

(14 reference statements)

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“…However, challenges persist in their use as restorative materials, including susceptibility to secondary caries and low mechanical properties. Recent studies indicate that the fluoride-releasing capability of conventional GICs may be insufficient for effective antibacterial conservation in many cases [ 17 ]. Consequently, various efforts have been made to enhance the antibacterial properties of GICs to prevent secondary caries.…”

Section: Discussionmentioning

confidence: 99%

Investigating the Potential of Acacia nilotica-Enriched Glass Ionomer Cement: An Analysis of Antimicrobial Activity and Compressive Strength

Paulraj,

et al. 2024

Cureus

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Background According to existing literature, introducing natural antibacterial agents into glass ionomer cement (GIC) has been associated with potential negative impacts on their strength properties. Hence, this study aims to explore the antibacterial effectiveness of glass ionomer cement enriched with Acacia nilotica and subsequently assess its compressive strength characteristics. Aim The objective of the study is to assess the antimicrobial effectiveness and compressive strength of glass ionomer cement modified with Acacia nilotica . Materials and methods The plant extract was incorporated into the conventional glass ionomer cement in three different proportions (powder GIC : extract: liquid GIC ), divided into group I, group II, and group III with ratios of 2:1:1, 3:1:2, and 3:2:1 respectively. Additionally, a control group denoted as group IV was included without any modifications. Subsequently, the specimens were prepared, and their chemical structure was analyzed using Fourier transform infrared spectroscopy (FTIR), followed by testing for antimicrobial activity using the minimum inhibitory concentration (MIC) assay against Streptococcus mutans and Lactobacillus . The assessment of compressive strength was conducted following ISO 9917-1:2007 standards, and the recorded values represent the maximum force the specimen could withstand before fracturing. Results The antimicrobial effectiveness against Streptococcus mutans and Lactobacillus exhibited a notable increase in all modified specimens compared to the control group, with a significance level of p<0.05. Additionally, significant improvements in compressive strength were observed in group III (183.49±2.99) when compared to the remaining groups. The higher concentrations of the plant extract resulted in superior outcomes. Conclusion Therefore, the incorporation of Acacia nilotica into GIC shows promising potential as a restorative material. These investigations can provide valuable insights into the material's performance and durability, contributing to its potential application in dental restorations. Future research is needed to thoroughly investigate the bonding chemistry between Acacia nilotica and GIC, as well as to assess the extent of microleakage.

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Section: Discussionmentioning

confidence: 99%

Investigating the Potential of Acacia nilotica-Enriched Glass Ionomer Cement: An Analysis of Antimicrobial Activity and Compressive Strength

Paulraj,

et al. 2024

Cureus

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“…Resistance to acidic challenges is crucial in ensuring the long-term durability of materials used in direct restorations. It has been shown that acidic conditions can have detrimental effects on tooth structure and restorative materials [ 13 ]. While adding antimicrobial agents to dental materials provides several therapeutic benefits, it frequently affects their physio-mechanical characteristics.…”

Section: Discussionmentioning

confidence: 99%

A Comparative In Vitro Analysis of Antimicrobial Effectiveness and Compressive Resilience in Chirata and Terminalia arjuna Modified Glass Ionomer Cement

Devi,

Paulraj,

George

et al. 2024

Cureus

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Background: Glass ionomer cements are commonly utilized in dental restorations due to their biocompatibility, strong chemical bond with dental tissues, and ability to resist tooth decay. However, their effectiveness can be compromised by the presence of persistent cavity-causing microorganisms. Therefore, it is essential to consider incorporating antibacterial agents into these restorative materials. Swertia chirayita (S. chirayita) and Terminalia arjuna (T. arjuna) are well-known for their rich composition of phytochemicals that can potentially inhibit the growth of bacteria. Hence, the current research is focused on modifying glass ionomer cement with Chirayita and T. arjuna extracts to enhance its antibacterial properties. Aim: This research aims to determine the antimicrobial efficacy and compressive strength of glass ionomer cement modified with Chirayita and T. arjuna extracts. Methodology: Plant extracts were prepared from both Chirayita and T. arjuna. The powder and liquid components of conventional glass ionomer cement (GIC) were mixed, followed by adding these extracts at three different concentrations. To assess antimicrobial properties, typical strains of Streptococcus mutans and Lactobacillus were employed to test both the modified GIC and unmodified GIC (used as a control). For Chirayita and T. arjuna-modified GIC, minimum inhibitory concentration (MIC) assays were conducted at three different concentrations. MIC was assessed at various time intervals ranging from 1 to 4 hours for modified and unmodified groups. Moreover, compressive strength was measured using cylindrical molds. The highest force exerted at the point of specimen fracture was recorded to calculate the compressive strength values in megapascal (MPa). Results: The antimicrobial efficiency of Chirata and T. arjuna-modified GIC was evaluated using a MIC assay, indicating a statistically significant enhancement in antimicrobial potency against S. mutans and Lactobacillus within the modified groups in contrast to the control group (p<0.05). However, there were no notable changes in compressive strength when comparing the control group to the modified groups (p>0.05). Conclusion: The antimicrobial effectiveness against S. mutans was observed to be greater in both T. arjuna and Chirayita-modified GIC. In the case of Lactobacillus, Chirayita-modified GIC exhibited more pronounced antimicrobial properties compared to T. arjuna. Importantly, both extracts did not alter the compressive strength of Conventional (unmodified) GIC. Hence, Chirayita-modified GIC appears to be a promising restorative material for combatting recurrent caries. Additional investigation is required to assess the material's stability over an extended period.

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“…11 Beberapa penelitian menunjukkan bahwa penambahan ekstrak etanol propolis (EEP) mampu meningkatkan efek antibakteri SIK. [12][13][14] Di sisi lain, modifikasi ini memiliki dampak negatif terhadap sifat mekanik SIK, seperti pengaruhnya dalam penurunan kekuatan tekan semen. 13,15 Diketahui bahwa modifikasi ini juga memengaruhi sifat fisik material, di antaranya mengurangi viskositas serta memperpanjang waktu kerja dan waktu pengerasan SIK.…”

Section: Pendahuluanunclassified

Evaluasi Perubahan Warna Semen Ionomer Kaca dengan Penambahan Ekstrak Etanol Propolis Trigona spp.

Pratiwi

Azalia

Hasan

et al. 2023

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Glass ionomer cement (GIC) is constantly modified to improve its properties and expand its use in dental practice. One of the modifications studied is the addition of ethanolic extract of propolis (EEP), a natural resin material with various pharmacological effects. Modifications made with EEP were found to increase the antibacterial effect of GIC, but this modified material also impacted the physical properties of the cement. This study aimed to evaluate the color change of GIC caused by the addition of EEP. This was a laboratory experimental study. The GIC color was assessed using the VITA Easyshade V spectrophotometer. A total of 20 cylindrical GIC samples measuring 10 mm (diameter) x 2 mm (height) were divided into four groups based on the proportion of EEP added to the GIC liquid, as follows: A, conventional GIC (control); B, GIC modified with EEP at 25% w/w; C, GIC modified with EEP at 30% w/w; and D, GIC modified with EEP at 35% w/w. The color assessment was performed after the samples were immersed in artificial saliva and incubated for 24 hours. The post hoc test between the three experimental groups and the control group showed a significant difference (p<0.05). The ΔE value between the three experimental groups and the control group showed a value greater than 3.3. In conclusion, the addition of EEP in the proportions of 25%, 30%, and 35% resulted in significant color change of GIC. Keywords: glass ionomer cement; ethanolic extract of propolis; Trigona spp.; discoloration Abstrak: Semen ionomer kaca (SIK) terus dimodifikasi untuk meningkatkan sifat dan memperluas penggunaannya dalam praktik kedokteran gigi; salah satunya ialah penambahan ekstrak etanol propolis (EEP), suatu bahan resin alami yang memiliki berbagai efek farmakologis. Modifikasi dengan EEP dapat meningkatkan efek antibakteri dari SIK, namun bahan modifikasi ini juga berdampak terhadap sifat fisik semen. Penelitian ini bertujuan untuk mengevaluasi perubahan warna SIK yang disebabkan oleh penambahan EEP Trigona spp. Jenis penelitian ialah eksperimental laboratorik. Warna diukur menggunakan spektrofotometer VITA Easyshade V. Sebanyak 20 sampel SIK silinder berukuran 10 mm (diameter) x 2 mm (tinggi) dibagi dalam empat kelompok uji berdasarkan proporsi EEP yang ditambahkan ke cairan SIK: A, SIK konvensional (kontrol); B, SIK modifikasi EEP 25% w/w; C, SIK modifikasi EEP 30% w/w; dan D, SIK modifikasi EEP 35% w/w. Pengukuran warna dilakukan setelah sampel direndam dalam saliva buatan dan diinkubasi selama 24 jam. Uji post hoc antara ketiga kelompok perlakuan dengan kelompok kontrol menunjukkan perbedaan bermakna (p<0,05). Nilai ΔE antara ketiga kelompok perlakuan dengan kelompok kontrol menunjukkan nilai yang lebih besar dibandingkan 3,3. Simpulan penelitian ini ialah penambahan EEP dalam proporsi 25%, 30%, dan 35% secara bermakna mengakibatkan perubahan warna SIK. Kata kunci: semen ionomer kaca; ekstrak etanol propolis; Trigona spp.; perubahan warna

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Antimicrobial Efficacy of Triphala and Propolis-modified Glass Ionomer Cement: An In Vitro Study

Cited by 8 publications

References 34 publications

Investigating the Potential of Acacia nilotica-Enriched Glass Ionomer Cement: An Analysis of Antimicrobial Activity and Compressive Strength

Investigating the Potential of Acacia nilotica-Enriched Glass Ionomer Cement: An Analysis of Antimicrobial Activity and Compressive Strength

A Comparative In Vitro Analysis of Antimicrobial Effectiveness and Compressive Resilience in Chirata and Terminalia arjuna Modified Glass Ionomer Cement

Evaluasi Perubahan Warna Semen Ionomer Kaca dengan Penambahan Ekstrak Etanol Propolis Trigona spp.

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