Antimicrobial effect of Korean propolis against the mutans streptococci isolated from Korean

Abstract

The aim of this study was to determine the optimal concentration of Korean propolis against clinical isolates of mutans streptococci (MS) from Koreans. The antimicrobial activity was evaluated using the minimum inhibitory concentration (MIC) and time-kill curves against mutans streptococci. The MIC(90) values of propolis for MS were 35 μg/ml. Propolis had a bacteriostatic effect on Streptococcus mutans ATCC 25175(T) and bactericidal effects on Streptococcus sobrinus ATCC 33478(T) at > 2 × MIC (70 μg/ml). These results suggest that the propolis can be used in the development of oral hygiene products for the prevention of dental caries.

Antimicrobial Effect of Ursolic Acid and Oleanolic Acid against Methicillin-Resistant Staphylococcus aureus

“…Our data showed that the antimicrobial effect of UA against the MRSA strains was stronger than that of OA (Table 1). This result coincided with previous reports that UA has a stronger antimicrobial effect against mutans streptococci (Kim et al, 2010(Kim et al, , 2011. The MIC90 values of UA and OA against 55 strains of mutans streptococci are 8 µg/ml and 2 µg/ml (Kim et al, 2010(Kim et al, , 2011.…”

“…This result coincided with previous reports that UA has a stronger antimicrobial effect against mutans streptococci (Kim et al, 2010(Kim et al, , 2011. The MIC90 values of UA and OA against 55 strains of mutans streptococci are 8 µg/ml and 2 µg/ml (Kim et al, 2010(Kim et al, , 2011. It was difficult to understand the strain-dependent antimicrobial activity of UA and OA, because the antimicrobial UA and OA mechanisms are unknown.…”

“…The PCR reaction products were electrophoresed on 1.5% agarose gels. Lanes: S, size marker (100 bp ladder); 1, S. aureus KCTC 1621 T ; 2, S. aureus KCOM 1588;3, S. aureus KCOM 1589;4, S. aureus KCOM 1590;5, S. aureus KCOM 1591;6, S. aureus KCOM 1592;7, S. aureus KCOM 1593;8, S. aureus KCOM 1594;9, S. aureus KCOM 1595;10, S. aureus KCOM 1596;11, S. aureus KCOM 1597;12, S. aureus KCOM 1598;13, S. aureus KCOM 1599;14, S. aureus KCOM 1600;15 are derivatives of triterpenoid saponins (Liu, 1995), have a higher degree of anti-bacterial activity against pathogenic bacterial strains such as Staphylococcus aureus, Pseudomonas aeruginosa, Enterococcus faecalis, Streptococcus mutans, and Streptococcus sobrinus (Fontanay et al, 2008;Kim et al, 2010Kim et al, , 2011. In contrast, the antimicrobial activity of UA and OA against MRSA is controversial (Horiuchi et al, 2007;Fontanay et al, 2008 S. aureus strains from Koreans were isolated using MRSAselective media (Winstanley et al, 1993).…”

Effects of fluoride and Aloe vera tooh gel in artificial white spot lesions in vitro

“…S. mutans, and it is an agent with large anticaries and antiperiodontitis action [12][13][14][15] . In vitro studies have demonstrated the antimicrobial effect of an Aloe vera based dentifrice, which promoted the growth inhibition of several oral microorganisms, such as S. mutans, S. sanguis, A. viscosus and C. albicans [16][17] .…”

Antimicrobial Effect of Carvacrol against Cariogenic and Periodontopathic Bacteria

“…구강조직세포는 in vitro 보다 in vivo 상태에서 화합물에 좀 더 저항성을 가지게 되는데, 그 이유는 구강조직세포가 in vivo 상태에서는 혈액을 통해 영양분을 지속적으로 공급 받을 수 있 어 재생능이 더욱 뛰어나기 때문이다 (Kim et al, 2011). …”