Antimicrobial Effect of Acacia Nilotica on Some Gram Positive and Gram Negative Bacteria

Abstract

Acacia nilotica is a plant has an inspiring range of medicinal uses. This plant contributes a number of groups among which are alkaloids, volatile essential oils, phenols and phenolic glycosides, resins, oleosins, steroids, tannins and terpenes, this study aims to: examine the antimicrobial action of ethanolic extraction from fruits and seeds of Acacia nilotica. Hot ethanol extract (48°C) of fruits and seeds obtained from Acacia nilotica, used in minimum bactericidal concentration (MBC), agar diffusion method to detect the antibacterial effect of the extract. Elucidate almost for all bacterial types used in this study, the concentration of 100mg/ml was the mostly effective concentration on bacteria (Staphylococcus aureus, Streptococcus pneumonia, and Proteus mirabilis); while the E. coli and Pseudomonas aeruginosa the concentration of 75 mg/ml was the effective concentration for both of them as an optimum concentration.

Phytochemical screening of Acacia nilotica extract: an in vitro study

“…4 In our study ,the phytochemical analysis done on methanol extract and compared with ethanol and aqueous extract of flower Acacia nilotica, results revealed aqueous extract showed the presence of all phytochemical tested whereas methanol and ethanol extract showed the absence of saponin and alkaloid respectively. 13 Ghanghro et al also confirmed presence of alkaloids, flavonoids, tannins, phenols, tannins, saponins and amino acids and they also found heavy metals like nickel (Ni), chromium (Cr), zinc (Zn), cobalt (Co), cadmium (Cd), copper (Cu), manganese (Mn) and iron (Fe). 1 The most perilous metal like Fe (3.97 ppm), Cd (below detection limit) and Mn (0.06 ppm) were detected within the permissible limit in acacia flower.…”