Antimicrobial Coatings Obtained in an Atmospheric Pressure Dielectric Barrier Glow Discharge

Paulussen, Sabine; Vangeneugden, Dirk; Goossens, Olivier; Dekempeneer, Erik

doi:10.1557/proc-724-n8.13

Cited by 4 publications

(3 citation statements)

References 15 publications

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“…In the case of fibroblasts, a good adhesion brings forward the possibility of optimum biosealing around the implant, which further avoids bacterial infiltration and infection [72,73]. The sealing has been also observed to be promoted by the lower bacterial adhesion, both of E. coli and S. aureus, in similar coatings [35,74,75]. This is due to the water retention of the coating, which in turn produces an antifouling effect, reducing the number of bacteria adhered.…”

Section: Discussionmentioning

confidence: 99%

“…Plasma polymerization has been widely used as a process for preparing biocompatible coatings, but until recently, the application was limited mostly to low-pressure plasma polymerization [32][33][34] or, alternatively, with atmospheric pressure plasma polymerization [35][36][37]. In the latter, either dielectric barrier discharges or plasma jets are employed, introducing monomers in the discharge by producing an aerosol which was led by the gas flow toward the surface of the material [38].…”

Section: Introductionmentioning

confidence: 99%

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One-Step Liquid Phase Polymerization of HEMA by Atmospheric-Pressure Plasma Discharges for Ti Dental Implants

et al. 2021

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Dental implants can fail due to various factors, in which bad tissue integration is believed to have a significant role. Specific properties of the implant surface, such as its chemistry and roughness, are of paramount importance to address specific cell responses, such as the adsorption of proteins, as well as the adhesion and differentiation of cells, which are suitable for biomaterial and tissue engineering. In this study, an acrylate-containing coating was produced on titanium surfaces through the atmospheric pressure plasma treatment of a liquid precursor, 2-hydroxyethyl methacrylate. A hydrophilic coating was obtained, showing retention of the monomer chemistry as assessed by FTIR analysis and XPS. Enhanced fibroblast adhesion and decreased Staphylococcus aureus and Escherichia coli adhesion were recorded, showing that this is a suitable method to produce biocompatible coatings with a reduced bacterial adhesion.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

One-Step Liquid Phase Polymerization of HEMA by Atmospheric-Pressure Plasma Discharges for Ti Dental Implants

et al. 2021

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“…This can be expected, since the refractive index is determined by the interaction of light with the electrons of the constituent atoms and plasma treatments may induce an increase in either electron density or polarizability, thus promoting an increase in the refractive index. In general, the refractive indices of hydrated commercial contact lenses vary in the range of 1.38–1.44, but other materials with high refractive indices (above 1.5) have been used to assist in decreasing lens thickness and are described in several patents . To the best of our knowledge, the increase of the refractive index after the plasma treatment was never reported.…”

Section: Discussionmentioning

confidence: 99%

Effect of plasma treatment on the performance of two drug‐loaded hydrogel formulations for therapeutic contact lenses

et al. 2014

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Although the plasma technology has long been applied to treat contact lenses, the effect of this treatment on the performance of drug-loaded contact lenses is still unclear. The objective of this work is to study the effect of nitrogen plasma treatment on two drug-loaded polymeric formulations which previously demonstrated to be suitable for therapeutic contact lenses: a poly-hydroxyethylmethacrylate (pHEMA) based hydrogel loaded with levofloxacin and a silicone-based hydrogel loaded with chlorhexidine. Modifications of the surface and the optical properties, and alterations in the drug release profiles and possible losses of the antimicrobial activities of the drugs induced by the plasma treatment were assessed. The results showed that, depending on the system and on the processing conditions, the plasma treatment may be beneficial for increasing wettability and refractive index, without degrading the lens surface. From the point of view of drug delivery, plasma irradiation at moderate power (200 W) decreased the initial release rate and the amount of released drug, maintaining the drug activity. For lower (100 W) and higher powers (300 W), almost no effect was detected because the treatment was, respectively, too soft and too aggressive for the lens materials.

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Recent developments in functional organic polymer coatings for biomedical applications in implanted devices

Yang,

Jia,

Zhao

et al. 2024

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Organic polymer coatings have been commonly used in biomedical field, which play an important role in achieving biological antifouling, drug delivery, and bacteriostasis. With the continuous development of polymer science, organic polymer coatings can be designed with complex and advanced functions, which is conducive to the construction of biomedical materials with different performances. According to different physical and chemical properties of materials, biomedical organic polymer coating materials are classified into zwitterionic polymers, non-ionic polymers, and biomacromolecules. The strategies of combining coatings with substrates include physical adsorption, chemical grafting, and self-adhesion. Though the coating materials and construction methods are different, many biomedical polymer coatings have been developed to achieve excellent performances, i.e., enhanced lubrication, anti-inflammation, antifouling, antibacterial, drug release, anti-encrustation, anti-thrombosis, etc. Consequently, a large number of biomedical polymer coatings have been used in artificial lungs, ureteral stent, vascular flow diverter, and artificial joints. In this review, we summarize different types, properties, construction methods, biological functions, and clinical applications of biomedical organic polymer coatings, and prospect future direction for development of organic polymer coatings in biomedical field. It is anticipated that this review can be useful for the design and synthesis of functional organic polymer coatings with various biomedical purposes.

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Antimicrobial Coatings Obtained in an Atmospheric Pressure Dielectric Barrier Glow Discharge

Cited by 4 publications

References 15 publications

One-Step Liquid Phase Polymerization of HEMA by Atmospheric-Pressure Plasma Discharges for Ti Dental Implants

One-Step Liquid Phase Polymerization of HEMA by Atmospheric-Pressure Plasma Discharges for Ti Dental Implants

Effect of plasma treatment on the performance of two drug‐loaded hydrogel formulations for therapeutic contact lenses

Recent developments in functional organic polymer coatings for biomedical applications in implanted devices

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