One-Step Liquid Phase Polymerization of HEMA by Atmospheric-Pressure Plasma Discharges for Ti Dental Implants

Abstract

Dental implants can fail due to various factors, in which bad tissue integration is believed to have a significant role. Specific properties of the implant surface, such as its chemistry and roughness, are of paramount importance to address specific cell responses, such as the adsorption of proteins, as well as the adhesion and differentiation of cells, which are suitable for biomaterial and tissue engineering. In this study, an acrylate-containing coating was produced on titanium surfaces through the atmospheric pressure plasma treatment of a liquid precursor, 2-hydroxyethyl methacrylate. A hydrophilic coating was obtained, showing retention of the monomer chemistry as assessed by FTIR analysis and XPS. Enhanced fibroblast adhesion and decreased Staphylococcus aureus and Escherichia coli adhesion were recorded, showing that this is a suitable method to produce biocompatible coatings with a reduced bacterial adhesion.

Cold plasma surface treatments to prevent biofilm formation in food industries and medical sectors

“…The obtained hydrophilic coatings decreased Staphylococcus aureus and Escherichia coli adhesion. These surfaces were produced for dental implant antiadhesive effectiveness (Buxadera-Palomero et al 2021).…”

Recent Advances in Functional Polymer Materials for Energy, Water, and Biomedical Applications: A Review

“…Currently, functional polymers and are experiencing a rapid and continuous progress as drug delivery and protein purification systems. Due to their diversity, surface and bulk properties, polymers are the most effective biomaterials applied in drug formulations and in drug delivery devices such as implants [133][134][135]. Recent drug delivery systems involve dendrimers, micelles, polymeric nanoparticles, liposomes, microcapsules, cell ghosts, and lipoproteins.…”

Application of Plasma Technology in Bioscience and Biomedicine

“…Buxadera and co-workers reported that the atmospheric pressure plasma jet polymerization of a liquid precursor, 2-hydroxyethyl methacrylate, on titanium yielded a coating with enhanced fibroblast adhesion and simultaneously decreased Staphylococcus aureus and Escherichia coli adhesion, which could be relevant for dental implants [1]. A different strategy was employed by Sardella et al, who compared plasma enhanced-chemical vapor deposition (PE-CVD) of polyethylene oxide (PEO)-like coatings generated either at low pressure and also aerosol-assisted atmospheric pressure PE-CVD.…”