Antimicrobial and Antihypercholesterolemic Activities of <i>Pulicaria gnaphalodes</i>

Naqvi, Syed Ali Raza; Shah, Syed Muhammad Ali; Kanwal, Laiba; Saeed, Muhammad; Haq, Atta ul; Nisar, Zonaira; Akram, Muhammad

doi:10.1177/1559325820904858

Cited by 17 publications

(11 citation statements)

References 13 publications

(16 reference statements)

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“…The Gram negative bacteria also offer more resistance to antibacterial agents as compared to the Gram positive bacterial strains such as S. typhi is one that cause severe food borne illness known as typhoid fever and is treated with a set of antibiotics instead of single antibiotic. 37 , 38 The results of the study were compared with the ciprofloxacin taken as standard antibacterial agent, it showed strong growth inhibition of P. aeruginosa with 25.5 ± 1.21 mm ZOI followed by 20.2 ± 1.10 mm ZOI against K. pneumonia , however some results were missed due to COVID-19 epidemic lockdown.…”

Section: Resultsmentioning

confidence: 99%

Phytochemical Analysis, Antioxidant and Antimicrobial Screening ofSeriphidium OliverianumPlant Extracts

et al. 2021

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The aim of this study was to investigate the phytochemicals using reverse-phase high pressure liquid chromatography (RP-HPLC), antioxidant, antifungal and antibacterial activities of Seriphidium oliverianum stem extracts. The extraction was carried out by conventional shaking process (CSP) and ultrasonic assisted process (UAP). The highest total phenolic contents (97.85 ± 0.735 mg gallic acid equivalent (GAE)/g sample) and flavonoid contents (188.15 ± 0.53 mg catechin equivalent (CE)/g sample) were found in methanol extract obtained by CSP. Antioxidant activity was investigated using DPPH° scavenging assay and reducing power assay. Methanol extract using UAP showed the highest DPPH° scavenging activity (79.95% ± 1.80%) followed by methanol and butanol extracts obtained through CSP. Moreover, methanol extracts using CSP showed highest reducing activity (1.032 ± 0.0205 absorbance). In-vitro antimicrobial activity was studied using most common infection causing fungal and bacterial strains. Anti-fungal activity of methanol extract using CSP showed the highest zone of inhibition (10.5 mm) against F. avenaceum fungal strain, while aqueous extracts obtained through showed the highest antibacterial activity (22 ± 1.32 mm zone of inhibition) against S. aureus. The results showed that the methanol stem extract of S. oliverianum is a valued candidate for further screening and could be processed for in-vivo infection induced animal trials.

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Section: Resultsmentioning

confidence: 99%

Phytochemical Analysis, Antioxidant and Antimicrobial Screening ofSeriphidium OliverianumPlant Extracts

et al. 2021

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“…Each sample’s activity was checked by measuring the zones of growth inhibition developed in millimeters with the help of a graduated scale. 34 …”

Section: Methodsmentioning

confidence: 99%

Antibacterial Activity of Tris NaCl and PBS Buffer Protein Extract ofCassia fistula,Saccharum officinarum,Albizia lebbeckandCymbopogon citratesAgainst Bacterial Strains

et al. 2021

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Medicinal plants are gaining popularity over synthetic medicines because antibiotic resistance demands the alternative source of medication. In the present research, the crude protein extraction of 4 medicinal plants Cassia fistula, Saccharum officinarum, Albizia lebbeck and Cymbopogon citrates was carried out. Crude protein extraction was done by 2 different buffers i.e. Tris NaCl buffer and PBS buffer. Protein confirmation was done by Bradford assay in the spectrophotometer. Antibacterial potential was checked and compared against Escherichia coli, Bacillus subtilis, Neisseria gonorrhoea, Bacillus cereus and Proteus mirabilis. Antibacterial assay was performed by disc diffusion method, agar well method and zones of inhibition were calculated. The study results indicated that Tris NaCl extracts’ antimicrobial potential is higher than that of the PBS buffer. On disc diffusion method the Tris NaCl buffer extracts of Cymbopogon citrates showed maximum zone of inhibition 11 mm and 9 mm against Bacillus subtilis and Bacillus cereus respectively and control chloramphenicol showed maximum zone of inhibition 26 mm against Bacillus subtilis. Cassia fistula showed maximum zone of inhibition of 7 mm against Bacillus cereus while Saccharum officinarum and Albizia lebbeck didn’t show the any antibacterial activity. On the other hand, Protein extracts from PBS buffer didn’t show zone of inhibition against any bacteria. Only Albizia lebbeck showed minute zone of inhibition against Neisseria gonorrhea. On well diffusion method, Cassia fistula Tris NaCl protein extract showed the maximum zone of inhibition 20 mm and 18 mm against Proteus mirabilis and Bacillus subtilis respectively. While Albizia lebbeck PBS protein extract showed the maximum zone of inhibition 19 mm and 17 mm against Bacillus subtilis and Bacillus cereus. The results revealed that the protein extract of Albizia lebbeck, Cymbopogon citrates and Cassia fistula can be used tosynthesize antimicrobial drugs to treat the bacterial infections.

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“…The composite scaffolds can recognize favorable mechanical strength hydrophilicity and appropriate degradation process. A natural polysaccharides chitosan is utilized in various clinical applications, involving wound healing, nerve regeneration, and bone repairing (Jiankang et al, 2009;Naqvi et. al., 2020).…”

Section: Silver Nanoparticlesmentioning

confidence: 99%

Recent progress in materials development and biological properties of GTR membranes for periodontal regeneration

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Chronic periodontal is a very common infection that instigates the destruction of oral tissue, and for its treatment, it is necessary to minimize the infection and the defects regeneration. Periodontium consists of four types of tissues: (a) cementum, (b) periodontal ligament, (c) gingiva, and 4) alveolar bone. In separated cavities, regenerative process also allows various cell proliferations. Guided tissue regeneration (GTR) is a potential procedure that favors periodontal regrowth; however, some limitations (such as ineffective hemostatic property, poor mechanical property, and improper biodegradation) are also associated with it. This review mainly emphasizes on the following areas: (a) a summarized overview of the periodontium and its immunological situations, (b) recently utilized treatments for regeneration of distinctive periodontal tissues; (c) an overview of GTR membranes available commercially, and the latest developments on the characterization and processing of GTR membrane material; and 4) the function of the different nonpolymeric/polymeric materials, which are acting as drug carriers, antibacterial agents, nanoparticles, and periodontal barrier membranes to prevent periodontal inflammation and to improve the strength of the GTR membrane.

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Antimicrobial and Antihypercholesterolemic Activities of Pulicaria gnaphalodes

Cited by 17 publications

References 13 publications

Phytochemical Analysis, Antioxidant and Antimicrobial Screening ofSeriphidium OliverianumPlant Extracts

Phytochemical Analysis, Antioxidant and Antimicrobial Screening ofSeriphidium OliverianumPlant Extracts

Antibacterial Activity of Tris NaCl and PBS Buffer Protein Extract ofCassia fistula,Saccharum officinarum,Albizia lebbeckandCymbopogon citratesAgainst Bacterial Strains

Recent progress in materials development and biological properties of GTR membranes for periodontal regeneration

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