Antimicrobial and Anti‐Inflammatory Intelligent Surfaces

Griesser, Hans J.; Hall, Heike; Jenkins, A. Toby A.; Griesser, Stefani S.; Vasilev, Krasimir

doi:10.1002/9781118181249.ch6

Cited by 9 publications

(5 citation statements)

References 219 publications

(186 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[1][2][3][4] For example, polymeric thin films have been widely used as coatings for biomaterials and biomedical devices as the film composition, functionality, structure (i.e., thickness and density) and mechanical properties can be tailored depending on the selection of polymers and film fabrication stratergy. 1,[5][6][7][8] The development of bioactive surfaces aimed at promoting specific interactions while minimizing non-specific interactions (i.e., low-fouling) are central to many biomedical applications, including drug delivery, 9,10 implantable devices, [11][12][13] tissue engineering, 14,15 biosensors, 16 diagnostics, 17 and protein purification. 18 Of particular importance is the interaction and adsorption of proteins on surfaces when in contact with biological environments, which ultimately governs the biofunctionality of the material and influences cellular interaction, structure and function.…”

Section: Introductionmentioning

confidence: 99%

“…Over the past few decades, research in biomedical science has focused on developing functional material interfaces that are biocompatible and that can be engineered for specific biointeractions. − For example, polymeric thin films have been widely used as coatings for biomaterials and biomedical devices as the film composition, functionality, structure (i.e., thickness and density) and mechanical properties can be tailored depending on the selection of polymers and film fabrication strategy. ,− The development of bioactive surfaces aimed at promoting specific interactions while minimizing nonspecific interactions (i.e., low-fouling) are central to many biomedical applications, including drug delivery, , implantable devices, − tissue engineering, , biosensors, diagnostics, and protein purification . Of particular importance is the interaction and adsorption of proteins on surfaces when in contact with biological environments, which ultimately governs the biofunctionality of the material and influences cellular interaction, structure, and function. , As a result, significant effort has been devoted to developing surface coating and modification approaches toward low-fouling bioactive surfaces. ,,− For example, both the grafting-to and -from approaches have been extensively used to prepare low fouling surfaces from hydrophilic and zwitterionic materials, with the low-fouling ability of the surfaces being closely correlated with their hydration layer near the surface. , The strength of this surface hydration is primarily related to the physiochemical properties of the polymers and their surface packing, including film thickness, packing density and chain conformation .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Low-Fouling, Biospecific Films Prepared by the Continuous Assembly of Polymers

et al. 2013

View full text Add to dashboard Cite

We report that the continuous assembly of polymers (CAP) approach, mediated by ring-opening metathesis polymerization (ROMP), is a facile and versatile technology to prepare engineered nanocoatings for various biomedical applications. Low-fouling coatings on particles were obtained by the formation of multicompositional, layered films via simple and efficient tandem CAP(ROMP) processes that are analogous to chain extension reactions. In addition, the CAP(ROMP) approach allows for the efficient postfunctionalization of the CAP films with bioactive moieties via cross-metathesis reactions between the surface-immobilized catalysts and symmetrical alkene derivatives. The combined features of the CAP(ROMP) approach (i.e., versatile polymer selection and facile functionalization) allow for the fabrication and surface modification of various types of polymer films, including those with intrinsic protein-repellent properties and selective protein recognition capabilities. This study highlights the various types of advanced coatings and materials that the CAP approach can be used to generate, which may be useful for biomedical applications.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Low-Fouling, Biospecific Films Prepared by the Continuous Assembly of Polymers

et al. 2013

View full text Add to dashboard Cite

show abstract

“…In the present chapter, our discussion focuses on superhydrophobic surfaces. For further information regarding other techniques, useful information can be found in the review by Griesser et al [7] and in the work by Siedenbediel and Tiller [8].…”

Section: Strategies On Surface Modification For Antibacterial Propertiesmentioning

confidence: 99%

Superhydrophobic Surfaces Toward Prevention of Biofilm- Associated Infections

Moran¹,

Méallet‐Renault²

2018

Bacterial Pathogenesis and Antibacterial Control

View full text Add to dashboard Cite

In this chapter, we briefly review the different strategies for surface modification as a method to fight against bacteria adhesion and biofilm formation. We focus on superhydrophobic materials and biofilm medical infections. We give some insights into common materials and preparation techniques for superhydrophobic surfaces before discussing recent bacteria interacting with superhydrophobic surfaces. These surfaces have indeed demonstrated great potential in preventing bacterial adhesion and biofilm formation due to the presence of micro-and nanostructures. Although much work has been done, further investigations are still required to improve the surface mechanical properties over time and to understand the underlying mechanism behind their antimicrobial and antifouling capability. Moreover, there is a lack of standard methodology for evaluating antibacterial properties, and biofilm prevention should be studied with longer incubation times. We strongly believe in the potential of superhydrophobic surfaces, and we encourage more research on its magnificent properties, especially for their advantages over other antimicrobial surfaces.

show abstract

“…functionalities. These groups create a water-solvated structure which forms a liquid-like surface with highly mobile disordered molecular chains [ 46 , 47 , 48 ]. For protein adsorption to occur, there must be a reduction in the dehydration entropic energy associated with the removal of surface bound water [ 45 ].…”

Section: Non-fouling Plasma Deposited Coatingsmentioning

confidence: 99%

Non-Equilibrium Plasma Processing for the Preparation of Antibacterial Surfaces

et al. 2016

View full text Add to dashboard Cite

Non-equilibrium plasmas offer several strategies for developing antibacterial surfaces that are able to repel and/or to kill bacteria. Due to the variety of devices, implants, and materials in general, as well as of bacteria and applications, plasma assisted antibacterial strategies need to be tailored to each specific surface. Nano-composite coatings containing inorganic (metals and metal oxides) or organic (drugs and biomolecules) compounds can be deposited in one step, and used as drug delivery systems. On the other hand, functional coatings can be plasma-deposited and used to bind antibacterial molecules, for synthesizing surfaces with long lasting antibacterial activity. In addition, non-fouling coatings can be produced to inhibit the adhesion of bacteria and reduce the formation of biofilm. This paper reviews plasma-based strategies aimed to reduce bacterial attachment and proliferation on biomedical materials and devices, but also onto materials used in other fields. Most of the activities described have been developed in the lab of the authors.

show abstract

Antimicrobial and Anti‐Inflammatory Intelligent Surfaces

Cited by 9 publications

References 219 publications

Low-Fouling, Biospecific Films Prepared by the Continuous Assembly of Polymers

Low-Fouling, Biospecific Films Prepared by the Continuous Assembly of Polymers

Superhydrophobic Surfaces Toward Prevention of Biofilm- Associated Infections

Non-Equilibrium Plasma Processing for the Preparation of Antibacterial Surfaces

Contact Info

Product

Resources

About