Antimicrobial activity, total phenolic content and flavonoid concentrations of Teucrium species

Abstract

In vitro antimicrobial activity of 21 crude extracts obtained from seven taxa of the genus Teucrium (T. chamaedrys, T. montanum, T. arduini, T. polium, T. scordium subsp. scordium, T. scordium subsp. scordioides and T. botrys) was tested against bacterial and fungal species. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined using a microdilution analysis method. Total phenolic content and flavonoid concentrations were measured spectrophotometrically. Total phenols were determined using Folin-Ciocalteu reagent and their amounts ranged from 28.49 up to 159.84 mg CA/g of extract (chlorogenic acid equivalent). The amounts of flavonoids ranged from 38.17 up to 190.45 mg RU/g of extract (rutin equivalent).The plant extracts showed greater potential of antibacterial than antifungal activity. A relationship was found between total phenolics and biological activity. The highest level of total phenols was measured in the methanol extracts, which demonstrated higher antimicrobial activity than acetone and ethyl acetate extracts. Staphylococcus aureus ATCC 25923 appeared to be the most sensitive organism. Our results indicate that Teucrium spp extracts are rich sources of phenolic compounds and are promising candidates for further development as natural antimicrobial agents.

Inhibitory effects of different medicinal plants on Candida albicans growth

“…Many authors reported that plant extracts showed higher efficacy against bacteria than against fungi. In a study by Stanković et al (26), C. albicans strains were inhibited only by extracts of Teucrium scordium and T. botrys. In general, plant extracts exhibited higher antibacterial activity than antifungal activity, which was also confirmed for extracts of Tilia rubra subsp.…”

Antifungal activity of some botanical extracts on Fusarium oxysporum

“…However, the effects of flavonoids on phytopatogenic fungi are not well documented. A few studies indicate that flavonoids are not correlated with antifungal activity [11] or can stimulate spore germination [15], while other authors found that extracts of some plant species are able to inhibit fungi and bacteria and that their ability is mainly due to flavonoids [16,17]. Only 2 flavonoids, pisatin and medicarpin, have been shown to be active against F. oxysporum.…”

“…has also been reported [11][12][13][14]. Contrasting results are reported in literature regarding the effect of flavonoids on antifungal activity.…”

“…Contrasting results are reported in literature regarding the effect of flavonoids on antifungal activity. Some authors [11,15] found that flavonoids were not correlated with antifungal activity while others [16,17] reported that the inhibition of fungi was mainly due to flavonoids. The aim of the present work was to evaluate the antifungal activity of water extracts of various plant species using phytochemical screening.…”

Phytochemicals and Antioxidant Study of Teucrium Chamaedrys (L.) Plant

“…Antimicrobial and antioxidant activity, total phenolic and flavonoid concentrations of Teucrium species have been studied by a number of researchers in the different parts of the world (Kucuk et al, 2006;Sarker et al, 2007Gursoy et al, 2009Nevcihan et al, 2009;Stanković et al, 2010;Kundaković et al, 2011;Stanković et al, 2012;Vlase et al, 2014).…”