Antimicrobial activity of ZnO nanoplates and its Ag nanocomposites: Insight into an ROS-mediated antibacterial mechanism under UV light

Joe, Ara; Park, Se-Ho; Kim, Dajung; Lee, Yeong-Ju; Jhee, Kwang-Hwan; Sohn, Youngku; Jang, Eue‐Soon

doi:10.1016/j.jssc.2018.08.003

Cited by 64 publications

(21 citation statements)

References 44 publications

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“…The high resolution C 1s spectrum was divided into three peaks ( Figure 8 c). The characteristic peaks at 284.088 and 289.13 eV can be attributed to the benzene ring and carboxylic acid groups on the organic ligand H 2 BDC in MIL-101(Fe), respectively [ 49 ].…”

Section: Resultsmentioning

confidence: 99%

MIL-101 (Fe) @Ag Rapid Synergistic Antimicrobial and Biosafety Evaluation of Nanomaterials

Zheng

Chen

et al. 2022

Molecules

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Metal-organic frameworks (MOFs), which have become popular in recent years as excellent carriers of drugs and biomimetic materials, have provided new research ideas for fighting pathogenic bacterial infections. Although various antimicrobial metal ions can be added to MOFs with physical methods, such as impregnation, to inhibit bacterial multiplication, this is inefficient and has many problems, such as an uneven distribution of antimicrobial ions in the MOF and the need for the simultaneous addition of large doses of metal ions. Here, we report on the use of MIL-101(Fe)@Ag with efficient metal-ion release and strong antimicrobial efficiency for co-sterilization. Fe-based MIL-101(Fe) was synthesized, and then Ag+ was uniformly introduced into the MOF by the substitution of Ag+ for Fe3+. Scanning electron microscopy, powder X-ray diffraction (PXRD) Fourier transform infrared spectroscopy, and thermogravimetric analysis were used to investigate the synthesized MIL-101(Fe)@Ag. The characteristic peaks of MIL-101(Fe) and silver ions could be clearly seen in the PXRD pattern. Comparing the diffraction peaks of the simulated PXRD patterns clearly showed that MIL-101(Fe) was successfully constructed and silver ions were successfully loaded into MIL-101(Fe) to synthesize an MOF with a bimetallic structure, that is, the target product MIL-101(Fe)@Ag. The antibacterial mechanism of the MOF material was also investigated. MIL-101(Fe)@Ag exhibited low cytotoxicity, so it has potential applications in the biological field. Overall, MIL-101(Fe)@Ag is an easily fabricated structurally engineered nanocomposite with broad-spectrum bactericidal activity.

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Section: Resultsmentioning

confidence: 99%

MIL-101 (Fe) @Ag Rapid Synergistic Antimicrobial and Biosafety Evaluation of Nanomaterials

Zheng

Chen

et al. 2022

Molecules

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“…The generation of intracellular reactive oxygen species (ROS) was determined using 2.7-dichorofluorescin diacetate (DCFH-DA) [26]. DCFH-DA passively enters the cell and reacts with ROS, to form the highly fluorescent compound DCF.…”

Section: Methodsmentioning

confidence: 99%

Effects of Pb(II) and Cr(VI) Stress on Phosphate-Solubilizing Bacteria (Bacillus SP. Strain MRP-3): Oxidative Stress and Bioaccumulation Potential

Shao

Teng

et al. 2019

IJERPH

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The aim of this work was to ascertain the effects of Pb(II) and Cr(VI) on bacterial growth, generation of reactive oxygen species (ROS), activities of superoxide dismutase (SOD), and catalase (CAT), as well as the localization of bioaccumulated heavy metals in a phosphate-solubilizing bacterium. The results showed that the ROS increased from 1.4-fold to 1.8-fold of control under Pb(II) stress and decreased from 1.6-fold to 1.1-fold of control under Cr(VI) stress corresponding to metal concentrations (0.5–5 mmol·L−1). The SOD activities were ROS dependent; however, the CAT activities increased under both Pb(II) and Cr(VI) stress, from 11.4 to 21.8 U·mg−1 and 11.4 to 32.9 U·mg-1, respectively. Intra/extracellular accumulation were investigated by scanning transmission electron microscopy with energy dispersive X-ray spectroscopy (STEM-EDS) and it was calculated that extracellular accumulated Pb accounted for 61.7–95.9% of the total accumulation, while extracellular accumulated Cr only accounted for up to 3.6% of the total accumulation. Attenuated total reflection/Fourier-transform infrared spectroscopy (ATR-FTIR) analysis confirmed that the functional groups involved in those extracellular accumulation were not located in the loosely bound extracellular polysaccharides substances.

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“…BC-TiO 2 nanocomposites have certain antibacterial activity against E. coli and S. aureus, good healing potential, faster speed of regenerative epithelialization and ability to accelerate wound contraction (Khalid et al, 2017b). ZnO NPs can kill bacteria through Zn ion (Zn 2+ ) release or ROS produced by photocatalysis (Joe et al, 2018). Based on maleic anhydride (MA) modified BC (BCM), the nZnO/BCM biocomposites were prepared using a simple and environmentally friendly method (Figure 5D), which not only showed excellent antibacterial activity against S. aureus and E. coli, but also prevented bacterial infection and promoted wound healing by accelerating reepithelization and wound contraction (Luo et al, 2020).…”

Section: Metal/metal Oxide Nanoparticlesmentioning

confidence: 99%

Latest Advances on Bacterial Cellulose-Based Antibacterial Materials as Wound Dressings

Luo

et al. 2020

Front. Bioeng. Biotechnol.

111

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At present, there are various wound dressings that can protect the wound from further injury or isolate the external environment in wound treatment. Whereas, infection and slow self-healing still exist in wound healing process. Therefore, it is urgent to develop an ideal wound dressing with good biocompatibility and strong antibacterial activity to promote wound healing. Bacterial cellulose is a kind of promising biopolymer because it can control wound exudate and provide a moist environment for wound healing. However, the lack of antibacterial activity limits its application. In this paper, the advantages of bacterial cellulose as wound dressings were introduced, and the preparation and research progress of bacterial cellulose-based antibacterial composites in recent years were reviewed, including adding antibiotics, combining with inorganic antibacterial agents or organic antibacterial agents. Finally, the existing problems and future development direction of bacterial cellulose-based antibacterial wound dressings were discussed.

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Antimicrobial activity of ZnO nanoplates and its Ag nanocomposites: Insight into an ROS-mediated antibacterial mechanism under UV light

Cited by 64 publications

References 44 publications

MIL-101 (Fe) @Ag Rapid Synergistic Antimicrobial and Biosafety Evaluation of Nanomaterials

MIL-101 (Fe) @Ag Rapid Synergistic Antimicrobial and Biosafety Evaluation of Nanomaterials

Effects of Pb(II) and Cr(VI) Stress on Phosphate-Solubilizing Bacteria (Bacillus SP. Strain MRP-3): Oxidative Stress and Bioaccumulation Potential

Latest Advances on Bacterial Cellulose-Based Antibacterial Materials as Wound Dressings

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