Antimicrobial Activity of Vitex Negundo Linn. (Nirgundi) Leaves Extract

Deogade, Meena Shamrao; Pandya, Tarulata; Prasad, Kethamakka Shivarama; Kale, Kunal; Tankhiwale, Nilima

doi:10.21276/jrtm.2016/206

Cited by 7 publications

(7 citation statements)

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“…Plant extract of Vitex negundo L. was the most effective (Padder & Ganaie, 2015) both against Streptococcus mutans (MIC -minimum inhibitory concentration = 0.37 µg/mL) and P. aeruginosa (MIC = 0.75 µg/mL). Deogade et al (2016) determined antibacterial activity of ethanol extract from leaves of V. negundo towards bacteria Escherichia coli, Staphylococcus aureus and Klebsiella pneumoniae, producing maximum inhibition zone of S. aureus (15 mm at the concentration of 80-100 mg/mL) and minimum ones of E. coli and K. pneumoniae (12 and 11 mm at the concentration of 100 mg/mL, respectively). The notable inhibiting activity of extract of this plant was due to its high content of phenols and flavonoids (Prashith & Raghavendra, 2014).…”

Section: Discussionmentioning

confidence: 99%

Antibacterial and fungicidal activities of ethanol extracts of 38 species of plants

et al. 2020

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Galenic preparations are broadly used against microorganisms pathogenic to humans, thought their poteintial in this aspect is not studied completely. In our in vitro experiment we studied the influence of alcohol tinctures from 38 species of plants on 15 species of bacteria and one species of fungus. Zones of growth inhibition of colonies measuring over 8 mm were observed during the use of ethanol extracts of Maclura pomifera against eight species of microorganisms (Escherichia сoli, Proteus mirabilis, Serratia marcescens, Yersinia enterocolitica, Salmonella typhimurium, Rhodococcus equi, Campylobacter jejuni and Corynebacterium xerosis), Ginkgo biloba – against eight species (Enterococcus faecalis, S. marcescens, Y. enterocolitica, Klebsiella pneumoniae, Listeria іnnocua, L. monocytogenes, Р. аeruginosa and C. jejuni), Genista tinctoria – against seven species (E. coli, Enterobacter aerogenes, Proteus mirabilis, K. pneumoniae, S. typhimurium, Р. аeruginosa and Rh. equi), Phellodendron amurense – against seven species (E. faecalis, S. marcescens, S. typhimurium, Rh. equi, C. jejunі, C. xerosis and Candida albicans), Berberis vulgaris – against seven species (P. mirabilis, S. marcescens, K. pneumoniae, S. typhimurium, C. jejuni, Р. аeruginosa and C. xerosis), Vitex negundo – against six species (E. faecalis, E. coli, P. mirabilis, K. pneumoniae, S. typhimurium and Rh. equi), Koelreuteria paniculata – against six species (E. faecalis, P. mirabilis, S. marcescens, S. typhimurium, C. jejunі and E. coli), Magnolia kobus – against six species (E. faecalis, E. coli, P. mirabilis, S. marcescens, S. typhimurium, C. jejunі and C. xerosis), Liriodendron tulipifera – against six species (K. pneumoniae, Listeria іnnocua, Р. аeruginosa, C. jejuni, Rh. equi and C. albicans), Clematis flammula – against six species (E. faecalis, P. mirabilis, L. monocytogenes, Р. аeruginosa, C. jejuni and C. xerosis), Wisteria sinensis – against five species (E. coli, S. typhimurium, L. monocytogenes, Rh. equi and C. albicans), Chimonanthus praecox – against five species (E. faecalis, S. marcescens, L. monocytogenes, C. jejuni and Rh. equi), Colchicum autumnale – against five species (S. marcescens, K. pneumoniae, L. ivanovi, L. monocytogenes and Р. аeruginosa). As a result of the study, these plants were found to be the most promising for further study of in vivo antibacterial activity. In the search of antibacterial and antifungal activities, the following plants were observed to be less promising: Ailanthus altissima, Aristolochia manshuriensis, Artemisia absinthium, Callicarpa bodinieri, Campsis radicans, Catalpa duclouxii, Celastrus scandens, Dictamnus alba, Eucommia ulmoides, Geranium sanguineum, Laburnum anagyroides, Nepeta racemosa, Parthenocissus tricuspidata, Polygonatum multiflorum, Prunus dulcis, P. laurocerasus, Ptelea trifoliata, Pteridium aquilinum, Quercus castaneifolia, Q. petraea iberica, Salvia officinalis, Securigera varia, Styphnolobium japonicum, Tamarix elongata and Vitex agnus-castus.

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Section: Discussionmentioning

confidence: 99%

Antibacterial and fungicidal activities of ethanol extracts of 38 species of plants

et al. 2020

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“…Owing to the uses and properties like antibacterial, analgesic, antiviral, antifungal, anti-helminthic, anti-inflammatory, and immune-enhancing effects. (27) Study performed by Deogade et al (27) 2016, in which various concentrations of Vitex negundo Linn. like 20mg/ml, 40mg/ml, 60mg/ml, 80mg/ml and 100mg/ml had been used.…”

Section: E N D O D O N T I C I N F E C T I O N C O N S I S T S O F a mentioning

confidence: 99%

“…which was found to be successful in showing its effectiveness in terms of its antibacterial effect and penetration ability in dentin. (27) Herbal extracts like Vitex negundo Linn. prove to be potential alternatives to commonly available irrigants for root canals of primary teeth and can be used in day to day practice with minimal side effects.…”

Section: E N D O D O N T I C I N F E C T I O N C O N S I S T S O F a mentioning

confidence: 99%

Evaluation of Antibacterial Efficacy of Vitex negundo Linn. extract as Root Canal Irrigant against Enterococcus faecalis and its penetration into Root Dentin: An in-vitro study

Gupta¹,

Thosar²,

Rathi³

et al. 2020

IJAM

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Introduction: The aim of this study was to evaluate the antibacterial efficacy of Vitex negundo Linn. extract as root canal irrigant against Enterococcus faecalis and its penetration into root dentin. Methods and Materials: Forty single rooted premolars were randomly divided into 4 groups: 3% Sodium hypochlorite (NaOCl), 2% Chlorhexidine (CHX) , 100mg/ml Vitex negundo Linn. and saline as control all mixed with Rhodamine B dye. Test samples were analysed for bacterial count before and after irrigation using absorbent paper points and the colony forming units were recorded and measured. Sectioning of the samples was performed at three levels 3mm,6mm,9mm from apex and then these samples were analysed using confocal laser scanning microscopy for penetration depth of the irrigant within the dentinal tubules. Paired t-test and ANOVA test were used to perform statistical analysis with level of significance set at 0.05 Results: The mean CFU/ml count of Enterococcus facealis reduced significantly in all the groups post irrigation. All the irrigants showed maximum penetration depth at coronal third level compared to middle and apical third level respectively. The penetration depth of NaOCl group was better when compared to CHX group and Vitex negundo Linn. group but the difference was statistically not significant. Conclusion: Although 3% NaOCl was the most effective irrigant, all agents exerted acceptable antimicrobial activity against Enterococcus faecalis and penetration depth within tubules of dentin.

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“…Antimicrobial potential of V. negundo Linn. Leaf ethanol extract were investigated against different bacterial cultures (E. coli, S. aureus and K. pneumoniae) by Deogade et al, (2016). 20 mg/ml, 40 mg/ml, 60 mg/ml, 80 mg/ml, 100 mg/ml of leaf extract was used to detect activity and found that the maximum zone of inhibition observed for S. aureus 15 mm at the concentration of 80 mg/ml and 100 mg/ml and for E. coli and K. pneumoniae maximum ZOI noted was 12 mm and 11 mm at 100 mg/ml concentration respectively.…”

Section: Antibacterial Activitymentioning

confidence: 99%

Phytochemical Screening and Antimicrobial Activity of Vitex negundo Leaf and Stem Extracts against Bacterial and Fungal Pathogens

Bameta¹,

Sanwal²,

Ambwani³

2019

Int.J.Curr.Microbiol.App.Sci

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Antimicrobial Activity of Vitex Negundo Linn. (Nirgundi) Leaves Extract

Cited by 7 publications

References 0 publications

Antibacterial and fungicidal activities of ethanol extracts of 38 species of plants

Antibacterial and fungicidal activities of ethanol extracts of 38 species of plants

Evaluation of Antibacterial Efficacy of Vitex negundo Linn. extract as Root Canal Irrigant against Enterococcus faecalis and its penetration into Root Dentin: An in-vitro study

Phytochemical Screening and Antimicrobial Activity of Vitex negundo Leaf and Stem Extracts against Bacterial and Fungal Pathogens

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