Antimicrobial activity of the methanolic leaf extract of &lt;i&gt;Tabernaemontana pachysiphon&lt;/i&gt; stapf. (Apocynaceae)

Uwumarongie, O H; Onwukaeme, D N; Obasuyi, Osahon

doi:10.4314/njnpm.v11i1.11872

Cited by 5 publications

(6 citation statements)

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“…World Health Organization (WHO) encourages countries to examine traditional medicine with a view to identifying and exploiting aspects that provide safe and effective remedies for different diseases (Akinyemi et al, 2002;Uwumaronngie et al, 2007). The investigated results obtained from this study support the WHO recommendations as it provides scientific evidence that the sub-fractions of aerial parts of C. pumila have antimicrobial activity.…”

Section: Resultssupporting

confidence: 71%

Antimicrobial activity of sennosides from Cassia pumila Lamk.

Sharma¹

2012

J. Med. Plants Res.

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Ayurveda recommends the application of different parts of Cassia pumila Lamk. plant species in the forms of paste, powder, juice, and decoction for treatment of various infections. The chloroform active sub-fraction and five sennosides were investigated for their antimicrobial activity by using microdilution method. The reported results indicated that sennoside D demonstrated maximum activity against Streptococcus pneumoniae (140 µg/ml) and sennoside B to Rhizoctonia bataticola (170 µg/ml). The present data show that C. pumila extract has activity against different types of infectious and toxic microorganisms. The active phytoconstituents could potentially be developed for use in the treatment and/or prevention of microbial diseases.

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Section: Resultssupporting

confidence: 71%

Antimicrobial activity of sennosides from Cassia pumila Lamk.

Sharma¹

2012

J. Med. Plants Res.

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“…The study exhibited adequate results, as four extracts from three species showed promising activity below 0.5 mg/mL against the parasite protozoan E. histolytica [ 1 ]. Additionally, Uwumarongie et al [ 141 ] evaluated the antiamoebic activity of T. pachysiphon root and stem bark extracts. The findings of their study showed relatively high antiamoebic activity against E. histolytica [ 141 ].…”

Section: Major Bioactive Components and Biological Activities Of mentioning

confidence: 99%

“…Additionally, Uwumarongie et al [ 141 ] evaluated the antiamoebic activity of T. pachysiphon root and stem bark extracts. The findings of their study showed relatively high antiamoebic activity against E. histolytica [ 141 ].…”

Section: Major Bioactive Components and Biological Activities Of mentioning

confidence: 99%

Major Bioactive Alkaloids and Biological Activities of Tabernaemontana Species (Apocynaceae)

Naidoo

Dewir

et al. 2021

Plants

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Several species belonging to the genus Tabernaemontana have been well researched and utilized for their wide-ranging biological activities. A few of the most prominent species include Tabernaemontana divaricata, Tabernaemontana catharinensis, Tabernaemontana crassa, and Tabernaemontana elegans. These species and many others within the genus often display pharmacological importance, which is habitually related to their chemical constituents. The secondary metabolites within the genus have demonstrated huge medicinal potential for the treatment of infections, pain, injuries, and various diseases. Regardless of the indispensable reports and properties displayed by Tabernaemontana spp., there remains a wide variety of plants that are yet to be considered or examined. Thus, an additional inclusive study on species within this genus is essential. The current review aimed to extensively analyze, collate, and describe an updated report of the current literature related to the major alkaloidal components and biological activities of species within the genus Tabernaemontana.

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“…8 Biologically, various extracts of T. pachysiphon have been shown to possess antimicrobial, anti-ulcer and opiate receptor binding activities. [9][10][11][12] The aqueous extract of the powdered stem bark at a dose of 5 g/kg, produced no signs of toxicity and death in mice. 13 Although most of the phytochemical work on T. pachysiphon has been concerned with the alkaloidal constituents of its various parts, fatty acids such as linoleic, myristic, oleic, palmitic and stearic acids were obtained from the seed oil.…”

Section: Introductionmentioning

confidence: 99%