Antimicrobial Activity of the Ethanol Extract from Rubus coreanum against Microorganisms Related with Foodborne Illness

Abstract

This study analyzed the antibacterial activity of a Rubus coreanum (Bokbunja) ethanol extract. The antimicrobial activity was determined by disc diffusion, minimum inhibitory concentration (MIC), and growth inhibition methods with seven kinds of bacteria related to foodborne illness (Bacillus cereus, Escherichia coli, Escherichia coli O157:H7, Listeria monocytogenes, Pseudomonas aeruginosa, Staphylococcus aureus, and Salmonella typhimurium). In the results, disc diffusions of the ethanol extract from R. coreanum (9.8-17.5 mm at 4,000 μg/disc) clearly showed the antimicrobial activity of the extract against all tested microorganisms. Rubus coreanum promoted an inhibitory effect as follows: E. coli O157:H7 ˃ P. aeruginosa ˃ L. monocytogenes ˃ E. coli ˃ S. aureus ˃ B. cereus ≥ S. typhimurium. In the MIC test, R. coreanum showed high antimicrobial effect against L. monocytogenes at 500 ppm. Moreover, the R. coreanum ethanol extract showed strong growth inhibition against microorganisms, similar to the MIC results. These results show that a R. coreanum ethanol extract has powerful antimicrobial activity against all tested microorganisms, suggesting that R. coreanum will be useful as a potential natural preservative.

Synergistic Effect of Rubus crataegifolius and Ulmus macrocarpa Against Helicobacter pylori Clinical Isolates and Gastritis

“…Unripened R. crataegifolius is extensively used in combination with other herbal preparations in food, beverages and in Korean folk medicine for its management of impotence, inflammatory, hepatotoxicity, enuresis, and allergic disease (Cha et al, 2001;Oh et al, 2007;Yang et al, 2008). The plant is also shown to possess antibacterial (Jeon et al, 2012) as well as antiulcer (Kim et al, 2011) activity. The main constituents of RF are polyphenols including sanguine, coreanoside-F1, nigaichigoside, gallic acid, and ellagic acid (Oh et al, 2007;Kim et al, 2011;Jeon et al, 2012;Lim et al, 2012).…”

“…The plant is also shown to possess antibacterial (Jeon et al, 2012) as well as antiulcer (Kim et al, 2011) activity. The main constituents of RF are polyphenols including sanguine, coreanoside-F1, nigaichigoside, gallic acid, and ellagic acid (Oh et al, 2007;Kim et al, 2011;Jeon et al, 2012;Lim et al, 2012). Among these, antioxidant phenolic compound ellagic acid possesses strong chemoprotective and anti-Helicobacter properties (Chung, 1998).…”

Influence of Extraction Duration on the Chemical Composition and Biological Activities of Essential Oil of Thymus pallescens de Noé

“…Escherichia coli, Salmonella spp., Staphylococcus aureus and Bacillus spp. are major food-poisoning bacteria [14]. Food preservatives are divided into inorganic compounds, organic compounds and natural food preservatives, but concerns over the risk and stability of inorganic and organic compounds are increasing [15].…”

Growth inhibition effect ofRubus coreanusMiquel onCandida albicans

“…구되고 있다 [3][4][5][6] . 이와 같이 복분자의 효능은 다양한 연구를 통해 구 체화 되고 유효성분에 대한 연구가 진행되고 있으나 7) , 구강세균에 대한 연구는 아직 미비한 실정이다.…”