Antimicrobial activity of super-oxidised water against oral microorganisms

Yamada, Kiyotaka; Yama, Mitsuru; Takaku, Yuichiro; Kakizawa, Takashi; Kimizuka, Ryuta; Okuda, K; Kato, Tsuyoshi

doi:10.1016/j.archoralbio.2010.03.002

Cited by 10 publications

(19 citation statements)

References 16 publications

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“…Another study found Parvimonas micra as a species involved in root canal infections to be highly susceptible [29]. The destroying potential of radical ions of oxygen as another oxygen species was more pronounced on F. nucleatum, Porphyromonas gingivalis, and Prevotella intermedia than on Streptococcus sobrinus [30]. The potential superinfecting species, especially the grampositive species Staphylococcus aureus and Enterococcus faecalis as well as Candida albicans, were less sensitive in general.…”

Section: Discussionmentioning

confidence: 98%

Effect of ozone on periodontopathogenic species—an in vitro study

2011

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The in vitro study was aimed to determine the effect of ozone on periodontopathogenic microorganisms. Ozone was generated for 6 s-2 × 24 s (corresponding to 0.56 mg-2 × 2.24 mg of ozone) against 23 mainly anaerobic periodontopathogenic species. Agar diffusion test was used as a screening method. Then, the killing activity was tested in a serum-free environment and with 25% v/v inactivated serum. Further, the effect of ozone on bactericidal activity of native serum was analyzed against Fusobacterium nucleatum, Porphyromonas gingivalis, and Aggregatibacter actinomycetemcomitans. Agar diffusion test showed a high efficacy of ozone against microorganisms, especially against Porphyromonas gingivalis. This result was confirmed by the killing tests; most of the strains in a concentration of 10(5) were completely eliminated after twofold 18-s application of ozone. Only four of the six potentially "superinfecting" species (Staphylococcus aureus, Enterococcus faecalis, Enterobacter cloacae, Candida albicans) survived in part. Addition of heat-inactivated serum reduced the killing rate of ozone by 78% after 6-s and by 47% after twofold 18-s exposures; no strain was completely eradicated after any application of ozone. The bactericidal effect of native serum was enhanced after application of ozone; no effect was visible on the included A. actinomycetemcomitans strain which was found to be completely resistant to the bactericidal action of serum. In conclusion, (a) ozone has a strong antibacterial activity against putative periodontopathogenic microorganisms, and (b) the bactericidal effect is reduced in the presence of serum. Ozone may have potential as an adjunctive application to mechanical treatment in periodontitis patients.

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Section: Discussionmentioning

confidence: 98%

Effect of ozone on periodontopathogenic species—an in vitro study

2011

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“…This result could be explained by the fact that radical anion of oxygen showed the effect on planktonic bacterial cells only. Yamada and others (2010) also observed that radical anion of oxygen did not have significant fungicidal effect.…”

Section: Resultsmentioning

confidence: 89%

“…Increasing temperature significantly affected APC, while processing time and Boxyl ® concentration did not affect the reduction of APC (Tables 2 and 3). Yamada and others (2010) reported that radical anion of oxygen had antimicrobial activity against cultured planktonic cells. However, active oxygen in Boxyl did not have a meaningful effect on bacterial cells attached on fresh blueberry.…”

Section: Resultsmentioning

confidence: 99%

Optimization of Hot Water Treatment for Removing Microbial Colonies on Fresh Blueberry Surface

Kim

Corbitt²,

Silva³

et al. 2011

Journal of Food Science

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“…Other studies show similar results in the composition of the sample. (31)(32)(33)(34)(35)(36)(37)(38) Gingivorrhagia is a clinical sign to bear in mind for it reveals the microbial activity and lysis of conjunctive tissue due to epithelial affectation and invasion of antigens of subgingival microbiota which activate the immune system at periodontal level. [29][30][31][32] Gingival bleeding, as it is also known, decreased considerably in our study, in the experimental groups treated with ozone therapy.…”

Section: Discussion Of Resultsmentioning

confidence: 99%

Therapeutic effects of Ozone therapy in adult periodontitis treatment, subtypes I and II.

2015

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Introduction. Conventional treatments of the periodontitis rely on surgery and antibioticotherapy. The properties of the ozone offer a more innocuous and more economic new alternative therapeutic. Objective. To evaluate the effectiveness of the ozone therapy in the treatment of periodontitis type I and II, and to identify the adverse events. Methods. It was carried out a clinical trial, phase III, randomized, controlled and to simple blind in patients that went to Odontological Clinic “III Congress of PCC” of Matanzas, January 2013 – January 2015. The sample belonged to 50 patients, divided in 5 groups of 10 patients each one: Group A – Treaties with ozone gas. Group B – OLEOZON®. Group C – ozonized water. Group D – treatment of ozone combined with the three modalities (gas, ozonized water and OLEOZON®. Group Z (control) – conventional treatment. The groups A, B, C and D were the experimental groups. Clinic and microbiolgical evaluation was measures. Effectiveness of the treatment, and adverse events were evaluated. The results showed up in graphics, the percentage and Square Chi were used. The ethical principles were completed. Results. Clinical evaluation went satisfactory to the month of the treatment in 84,6% of the studied places, with better results in the group D (96%), with significant differences between the experimental groups and the control. The microbiological evaluation was satisfactory and increased to 85,4% to the six months of the study. The experimental group D prevailed (96,6%). The effectiveness was good in 85,4% of the sample, prevailing in the experimental group D with 96,6%, followed by the group A. The percentage of adverse events was low, 1,5%. Conclusions. The clinical and microbiological evaluation showed satisfactory results, associated to a low percentage of adverse events (with gas ozone only). The combined ozone therapy was the most effective treatment for this type of periodontitis.

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Antimicrobial activity of super-oxidised water against oral microorganisms

Cited by 10 publications

References 16 publications

Effect of ozone on periodontopathogenic species—an in vitro study

Effect of ozone on periodontopathogenic species—an in vitro study

Optimization of Hot Water Treatment for Removing Microbial Colonies on Fresh Blueberry Surface

Therapeutic effects of Ozone therapy in adult periodontitis treatment, subtypes I and II.

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