Antimicrobial Activity of Some Essential Oils on Candida Genus Clinical Isolates

Kryvtsova, Maryna; Kohuch, T.T.; Саламон, Іван; Spivak, N. Ya.

doi:10.15407/microbiolj80.04.003

Cited by 8 publications

(5 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Marino et al (1999) determined the high antibacterial effect of essential oils of Thymus vulgaris L. against common bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Enterococcus faecalis, Salmonella typhimurium, Escherichia coli and Staphylococcus aureus). Our previous studies showed high antimycotic activity of essential oils against Candida genus microscopic fungi (Kryvtsova et al, 2017(Kryvtsova et al, , 2018Salamon et al, 2017). The antimicrobial effect of essential oils against oral cavity pathogens was shown in (Koba et al, 2011).…”

Section: Discussionmentioning

confidence: 94%

Compositions of essential oils with antimicrobial properties against isolates from oral cavities of patients with inflammatory diseases of the periodontium

Kryvtsova

Kostenko

Саламон

2018

Regul. Mech. Biosyst.

Self Cite

View full text Add to dashboard Cite

The significant spread of antibiotic-resistant microorganisms which are part of microbial associations of the oral cavity is considered one of the main causes for the complications and relapses of inflammatory diseases of the periodontium. This problem underlines the importance of constant monitoring of the circulation of polyantibiotic-resistant isolates, and development of new approaches and means of correction for the microbiocoenosis of the oral cavity affected by inflammatory processes. The paper is dedicated to research of antimicrobial properties of essential oil compositions against opportunistic pathogenic microorganisms, agents of inflammatory diseases of the periodontium. Out of the microorganisms isolated from the nidus of inflammation, the extra antibiotic-resistant ones were chosen. For the purpose of antibiotic susceptibility and antimicrobial activity testing, the disc diffusion method was used. The following compositions were manufactured from essential oils: Hyssopus officinalis L. + Rossmarinus officinalis L.; Menta piperita L. + H. officinalis; R. officinalis + Coriandrum sativum L.; R. officinalis + M. piperita + H. officinalis. The compositions H. officinalis + R. officinalis; M. piperita + H. officinalis were shown to have the highest level of antibacterial activity against clinical and typical isolates. Combinations of essential oils demonstrated a broader spectrum of activity against microorganisms than their components taken separately. Certain essential oils and the compositions H. officinalis + R. officinalis; M. piperita + H. officinalis were ascertained to have a high anti-mycotic activity against Candida genus microscopic fungi. This fact proves the advantage of application of combinations of essential oils compared to the use of their separate components. However, not all variants reviewed showed additive antimicrobial effect of the use of combinations of essential oils. The compositions that showed high antibacterial properties against the reviewed isolates may be used for oral hygiene products.

show abstract

Section: Discussionmentioning

confidence: 94%

Compositions of essential oils with antimicrobial properties against isolates from oral cavities of patients with inflammatory diseases of the periodontium

Kryvtsova

Kostenko

Саламон

2018

Regul. Mech. Biosyst.

Self Cite

View full text Add to dashboard Cite

show abstract

“…The selected literature data on anthocyanins raised the hope for their wide-spread use for the prevention and therapy of many diseases [14]. In our preceding works, we showed the antimicrobial activity of materials obtained from vegetable matter, phytoextracts and essential oils that showed the antimicrobial activity against isolates from the oral cavity, pharynx, and respiratory tract, including antibiotic-resistant ones [23][24][25][26].…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial, Antioxidant and some Biochemical Properties of Vaccinium vitis-idaea L.

Кривцова¹,

Kryvtsova²,

Trush³

et al. 2019

Mikrobiol. Z.

Self Cite

View full text Add to dashboard Cite

Over the past years there has been a growing interest to vegetable raw materials evaluated from the viewpoint of their potential antimicrobial activity. Vaccinium genus plants are known to contain a whole spectrum of biologically active substances with anti-inflammatory, antidiabetic, gene-protective, antioxidant and antimicrobial properties. The purpose of the work was to study the antimicrobial, antioxidant and some biochemical properties of alcoholic extracts of fruit and leaves of Vaccinium vitis-idaea L., gathered in the Ukrainian Carpathians. Methods. The plants for the study were gathered around the village of Pylypets, Mizhhiria rayon, Zakarpatska oblast (Transcarpathia). From the fruit and leaves, ethyl and methyl extracts were produced. The subjects for study were their antioxidant activity (by DPPH method), total tannin and flavonoids (by spectrophotometric method), and antimicrobial activity (by diffusion-into-agar method). For the purpose of study, type and clinical isolates were used from the oral cavity of human patients suffering from inflammatory diseases of periodontium, characterized by wide resistance spectrum to antibiotics. Results. The reviewed extracts were observed to have a higher antimicrobial activity against Gram-positive bacteria. The highest antimicrobial activity was shown by the extract of Vaccinium vitis-idaea L. fruit. Its antimicrobial activity was registered upon both test and clinical isolates of S.aureus, including methicillin-resistant ones. The ethyl fruit extract and methanol leaf extract were established to show high antimicrobial effect upon S.pyogenes. The ethanol fruit and leaf extracts and methanol fruit extract were observed to show weak antimycotic activity. The extracts were characterized by high antioxidant activity, with the highest effect peculiar for ethyl leaf and fruit extracts, and somewhat lower one for methyl extracts. The ethanol fruit extract was characterized by the highest tannin level out of all extracts under review. Conclusions. The antimicrobial and high antioxidant activity of the ethanol extract of Vaccinium vitis-idaea L. fruit and leaves, and absence of the antimicrobial effect against the probiotic strain of Lactobacillus plantarum, characterized by the antagonistic activity against opportunistic microorganisms, cause the advisability of their complex application as the basis for phytobiotics.

show abstract

“…Одним з перспективних, на нашу думку, альтернативних методів лікування кандидозів, є використання біологічно активних речовин природного походження. Зокрема, позитивні результати у лікуванні резистентних до анти-біотиків кандидозів слизистих ротової порожнини показали ефірні олії (Kryvtsova et al 2018). Окрім ефірних олій, позитивний результат було отримано і в досліді дії фітопрепаратів на пародонтит, викликаний різними інфекційними агентами, в тому числі й асоціаціями кандиди з умовно патогенними бактеріями (Kryvtsova 2019;Kryvtsova, Kostenko 2019;Kryvtsova, Kostenko 2020).…”

Section: вступunclassified

Antibiotic Susceptibility of Fungal and Bacterial Communities From Infected Gunshot Wound Surfaces

KOLESNYK,

KRYVTSOVA,

KOLESNYK

et al. 2023

Scientific Bulletin of the Uzhhorod University. Series Biology

View full text Add to dashboard Cite

The publication presents part of our research on antibiotic sensitivity of microbial communities in purulent wounds of wounded soldiers treated in medical institutions in Transcarpathia (Zakarpatska Oblast, Ukraine). In 32.2% of the samples obtained from the purulent wounds, associations of microscopic fungi Candida glabrata with a different spectrum of opportunistic bacteria were identified. In no case was Candida glabrata detected as a monoculture; the fungi were found only in association with bacteria. In total, our studies identified four associations of Candida glabrata with bacteria. Three of these associations were found to be two-component: Candida glabrata + Staphylococcus aureus; Candida glabrata + Pseudomonas spp. and Candida glabrata + Klebsiella spp.; one was three-component: Candida glabrata + Staphylococcus aureus + Enterobacter spp. The study of sensitivity to 30 antibiotics and 5 antifungal drugs used in medical institutions showed a significant level of resistance of the isolated microorganisms to antibiotics. Groupings involving fungi and bacteria exhibit complex resistance and pose a problem because the elimination or reduction of the persistence of one of the associates does not solve the problem of infection, but merely leads to the transformation of the grouping. In such circumstances, research into the antibiotic sensitivity of all microbial associates isolated from the inflammatory site and selection of the optimal treatment protocol becomes especially important. Along with the search for the dosing schedule of new antibiotics and antifungal drugs, it is necessary to look for alternative biologically active compounds with antimicrobial properties.

show abstract

Antimicrobial Activity of Some Essential Oils on Candida Genus Clinical Isolates

Cited by 8 publications

References 9 publications

Compositions of essential oils with antimicrobial properties against isolates from oral cavities of patients with inflammatory diseases of the periodontium

Compositions of essential oils with antimicrobial properties against isolates from oral cavities of patients with inflammatory diseases of the periodontium

Antimicrobial, Antioxidant and some Biochemical Properties of Vaccinium vitis-idaea L.

Antibiotic Susceptibility of Fungal and Bacterial Communities From Infected Gunshot Wound Surfaces

Contact Info

Product

Resources

About