Antimicrobial Activity of Microalgae Isolated from Fresh Water Pond, Tamil Nadu, India

Mugilan, V.; Sivakami, R.

doi:10.20546/ijcmas.2016.506.063

Cited by 3 publications

(3 citation statements)

References 16 publications

(5 reference statements)

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“…These finding somehow has an agreement with previous studies that indicated methanol extracts of Lyngbya kuetzingiana and Nostoc linckia had moderate antibacterial activities 21,22 . While studying the MIC of different isolated, purified compounds of the isolates, through the broth dilution method, it was observed that the MIC values ranged between 0.312-5mg/ml Table 3.…”

Section: Characterization and Identification Of Bioactivesupporting

confidence: 93%

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2021

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Background and Objectives: Cyanobacteria are rich in various bioactive compounds. This study aims to screen the antimicrobial activity of subaerial Cyanobacteria isolated from sub-aerial habitats (Old monuments and building facades). Materials and Methods: Crude aqueous and organic extracts were screened for phytochemical constituents and tested for their antimicrobial efficacy against human pathogens. The crude extract that showed better antimicrobial activities were further fractionated by column chromatography and purified by TLC. The active bands were scraped out separately and concentrated in vacuo to isolate pure compounds. Each purified compounds dissolved in respective solvents, assayed for antimicrobial activities were further characterised through FTIR and LC-MS. Results: The results indicated the presence of many secondary metabolites. Of the isolated purified compounds, the compounds from three species, viz. Scytonema hyalinum, Tolypothrix rechingeri, and Fischerella species exhibited antimicrobial activities, whereas others showed antibacterial activity. The FTIR spectra revealed the peaks of carboxylic acid, alkaloids, and phenolic compounds. The chemical compounds were identified as 1,3-dihydroxycyclohexane [Lyngbya kuetzingiana], 4-(4-hydroxyphenyl) butanoic acid [Nostoc linckia], octahydro-1H-indole-2-carboxylic acid [Scytonema sp., S. pseudoguyanensis, S. pseudohofmani], ergost-5-en-3-ol [Scytonema hyalinum],7,11-dihydroxysolasodine [Scytonema ocellatum], 2, 4-Bis (2-methyl-2-propanyl)phenol-phosphorous acid [Tolypothrix rechingeri] and Pentaphenyl ferrocene carboxamide [Fischerella sp.] respectively. Conclusion:Though it is firsthand information regarding the isolation of sub-aerial Cyanobacteria, with a production of different bioactive chemical compounds, further investigation is required for use in pharmaceutical industries against costly harmful antibiotics and chemotherapeutics. INTRODUCTION:The development of multidrug resistance (MDR) among pathogens is a global concern today. This necessitates the demand for the discovery of the new source of chemical compounds as alternative antibiotics.

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Section: Characterization and Identification Of Bioactivesupporting

confidence: 93%

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2021

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“…Literature stresses isolation and identification of Cyanobacteria from a diverse environment with bioactivities, but only few research has focused on a variety of bioactive compounds produced by Cyanobacteria after analysis of a great number of marines [41][42][43], freshwater [44][45][46], terrestrial [47,48], and hot spring [49,50]. Cyanobacterial natural products still seem to prevail followed at much lesser proportions by alkaloids, aromatic compounds, cyclic depsipeptides, cyclic peptides, cyclic peptide, cyclophane, fatty acids, linear peptides, lipopeptides, nucleosides, phenols, macrolides, polyketides, polyphenyl ethers, porphinoids and terpenoids [51].…”

Section: Bioactive Compounds From Cyanobacteriamentioning

confidence: 99%

Sub-Aerial Cyanobacteria: A Survey of Research with Antimicrobial Properties for Pharmaceutical Approaches

Singh¹

2022

Focus on Bacterial Biofilms

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Cyanobacteria also known as Blue Green Algae (BGA) are widely distributed in environments. Cyanobacteria or BGA commonly being aquatic are also reported from terrestrial ecosystems like sub-aerial surface of temples, monuments and building facades etc., represent their versatile habitats and extremophilic nature. These organisms are the excellent material for primary and secondary metabolites has been investigated by ecologists, physiologists, biochemists and molecular biologists. Scientists and young researchers require knowledge of the potential cyanobacteria and their exploitation in order to formulate effective natural compound or drug remedies. A large number of reports in literature stress have acknowledged the use of Cyanobacteria in pharmaceutical and industries, due to the production of different secondary metabolites with diverse bioactivities. However, very less study is being carried out with respect to exploitation of these sub-aerial Cyanobacteria group for production of different secondary metabolites with biological activities. Since many cyanobacteria are also able to survive most type of stress/and or extreme, they may become even more important as antimicrobial agents of pharmaceuticals in the future. Hence, special attention is paid to these groups of organisms.

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“…The effects of plant extracts on bacteria have been studied by a very large number of researchers in different parts of the world 12 . Much work has been done on ethnomedicinal plants in India 13 . Plants are rich in a wide variety of secondary metabolites such as tannins, terpenoids, alkaloids, flavonoids, glycosides, etc., which have been found in-vitro to have antimicrobial properties 14,15 .…”

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2022

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Background and Objectives: This study was carried out with the objective to investigate the antibacterial and antifungal activity of the bark of Hardwickia binata Roxb. Materials and Methods: Methanolic extract of bark of Hardwickia binata Roxb. exhibited an inhibitory effect towards the pathogenic organisms. Antimicrobial activity the zone of inhibition values of methanolic extract of bark of Hardwickia binata Roxb. in against two Grampositive microorganisms viz. Staphytococcus aureus and Bacillus subtilis and two Gram negative microorganisms viz. Escherichia coli and Pseudomonas aeruginosa showed significant activity. Antifungal activity of methanolic extract of bark of Hardwickia binata Roxb. in against two microorganism, Candida albicans, and Aspergillus niger, showed significant activity. Results: The results showed that the remarkable inhibition of the bacterial growth was shown against the tested organisms. The phytochemical analyses of the plants were carried out. The microbial activity of the Hardwickia binata was due to the presence of various secondary metabolites. Conclusion: Hence, these plants can be used to discover bioactive natural products that may serve AS leads in the development of new pharmaceuticals research activities.INTRODUCTION: Antibiotics are one of our most important weapons in fighting bacterial infections and have greatly benefited the healthrelated quality of human life since their introduction. However, over the past few decades, these health benefits are under threat AS many commonly used antibiotics have become less QUICK RESPONSE CODE

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Antimicrobial Activity of Microalgae Isolated from Fresh Water Pond, Tamil Nadu, India

Cited by 3 publications

References 16 publications

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Sub-Aerial Cyanobacteria: A Survey of Research with Antimicrobial Properties for Pharmaceutical Approaches

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