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Abstract

Background and Objectives: This study was carried out with the objective to investigate the antibacterial and antifungal activity of the bark of Hardwickia binata Roxb. Materials and Methods: Methanolic extract of bark of Hardwickia binata Roxb. exhibited an inhibitory effect towards the pathogenic organisms. Antimicrobial activity the zone of inhibition values of methanolic extract of bark of Hardwickia binata Roxb. in against two Grampositive microorganisms viz. Staphytococcus aureus and Bacillus subtilis and two Gram negative microorganisms viz. Escherichia coli and Pseudomonas aeruginosa showed significant activity. Antifungal activity of methanolic extract of bark of Hardwickia binata Roxb. in against two microorganism, Candida albicans, and Aspergillus niger, showed significant activity. Results: The results showed that the remarkable inhibition of the bacterial growth was shown against the tested organisms. The phytochemical analyses of the plants were carried out. The microbial activity of the Hardwickia binata was due to the presence of various secondary metabolites. Conclusion: Hence, these plants can be used to discover bioactive natural products that may serve AS leads in the development of new pharmaceuticals research activities.INTRODUCTION: Antibiotics are one of our most important weapons in fighting bacterial infections and have greatly benefited the healthrelated quality of human life since their introduction. However, over the past few decades, these health benefits are under threat AS many commonly used antibiotics have become less QUICK RESPONSE CODE