Antimicrobial Activity of <i>Crinum d</i><i>efixum</i> Ker - Gawler Leaves

Abstract

Crinum defixum Ker - Gawler is a bulbous herb which has widely used in indigenous medicine for many diseases; mainly leaf and bulb extracts are of medicinal importance. Leaf extract is used as a treatment for pimples, body-ache, dropsy, carbuncle, paronychia, leprosy, fever and diarrhoea. The bulbs are crushed and applied on to piles and itching. The present study to determine the possible phytochemicals and antimicrobial activity of various leaf extracts of Crinum defixum Ker - Gawler plant. The phytochemical screening demonstrated the presence different types compound like flavonoids, tannins, phenolic compounds, saponins and glycosides. The ethanol, methanol and crude extracts of Crinum defixum Ker - Gawler showed significant antibacterial activity against Escherichia coli, Staphylococcus aureus, pseudomonas aeruginosa, proteus vulgaris and antifungal activity against Candida albicans, Aspergillus flavus when compare to different concentrations (μg/mL). The antimicrobial potential of test compounds was determined on the basis of mean diameter of zone of inhibition around the disk in millimetres. Thus, the present findings revealed the medicinal potential of Crinum defixum Ker - Gawler to develop a drug against various human ailments.

GCMS, phytochemicals and antioxidant activities of in vitro callus extracts of Strobilanthes kunthiana (Nees) T. Anderson ex Benth: An endemic plant of Acanthaceae

“…The prevailing major compounds were 9,12-octadecadienoic acid (Z,Z) (50.32%) which act as antiinflammatory, antiarthritic, antioxidant, anticancer (Mangunwidjaja et al, 2006) hypocholesterolemic, cancer preventive, hepatoprotective, nematicide, insectifuge, antihistaminic, antieczemic, antiacne, 5-alpha reductase inhibitor, antiandrogenic anticoronary insectifuge (Rajeswari et al, 2012) antiarteriosclerotic, antianaphylactic, antiprostatic (Rajeswari andSrinivasan, 2015). hexadecanoic acid, methyl ester (20.69%) similar percentage (21.25%) were reported in Tesium humile (Belakhdar et al, 2015) and it contains many biological activity such as antioxidant, hypocholesterolemic, nematicide, pesticide, antiandrogenic flavor, hemolytic,5-alpha reductase inhibitor, antifibrinolytic, lubricant, antialopecic (Selvan and Velavan 2015), anti-inflammatory (Hema et al, 2011), cancer preventive, hepatoprotective, antihistaminic, antieczemic, antiachne, antiarthiritic, anticoronary (Krishnamoorthy andSubramaniam, 2014), antibacterial, antifungal (Chandrasekaran et al, 2011). 9-Octadecenoic acid (Z)-, methyl ester is reported to have antiinflammatory, antiandrogenic, cancer preventive, dermatitigenic, hypocholesterolemic, 5-alpha reductase inhibitor, anemiagenic, insectifuge (Rajeswari and Rani, 2015 ), antioxidant, anticancer (Asghar et al, 2011;Hema et al, 2011).…”

“…Secondary metabolites of plants serve as defense mechanism against predation by many microorganism, insects and herbivores. These secondary metabolites contribute many biological activities such as anti-inflammatory, antioxidants, antiosteoartritic, analgesic activities, antidiabetic, antimicrobial and heptaprotective (Desu et al, 2011;Singh, 2014).…”

“…It is a shrub that grow abundantly in the Shola forest of Western Ghats in South India (Paulsamy et al, 2007;Moylan et al, 2004) S. kunthiana is well known to possess both ornamental and medicinal properties. The abundant source of unique active components shows antiinflammatory, anti-osteoarthritic (Desu et al, 2011), analgestic properties (Desu et al, 2012 anticancer activity and antioxidant (Singh et al, 2014), antibioflim activity (Everlyne et al, 2016), enzyme inhibitor, central nervous depressant activity (Rajasekaran et al, 2000), antigiardial activity (Singh et al, 2012) antifungal, antibacterial, antiseptic, hypocholesterolemic 5-alpha reductase inhibitor, antimicrobial, cytotoxicity, protect skin against UV (Everlyne et al, 2015).…”

B:Gas Chromatography-Mass Spectrometry Analysis of Marine Seagrass Thalassodendron ciliatum Collected from Red Sea

“…For unsaturated long chain fatty acids of C-20, cis-11-eicosenoic acid was the most active antioxidant fatty acid followed by 8,11,14-eicosatrienoic acid which manifested also a significant inhibition of COX-II enzyme activity, inflammation causing enzyme (Henry et al, 2002). antioxidant, antimalarial activities (Costantino et al, 1993;Elaiyaraja and Chandramohan, 2016). 1-Hexacosanol was found to have larvicidal activity against Chromolaena odorata through acetylcholinesterase inhibition mechanism (Gade et al, 2017).…”

Estudio fitoquímico preliminar y evaluación de la actividad antibacteriana del extracto metanólico de los bulbos de Crinum moorei Hook F.

“…La administración indiscriminada de antibióticos para el tratamiento de algunos procesos infecciosos ha conllevado a un incremento de la resistencia de ciertas bacterias, representando un problema de salud pública. Esta situación ha propiciado la búsqueda de nuevas estrategias terapéuticas por parte de las diferentes organizaciones científicas e industria farmacéutica a nivel mundial, promoviendo con esto el descubrimiento de nuevas moléculas activas provenientes de fuentes naturales [1][2][3].…”