Antimicrobial Activity of 4-O-methylgallic Acid Isolated from Phyllanthus polyphyllus L. against Foodborne Pathogenic Bacteria and Yeasts

The α-glucosidase inhibitory activity of avicularin and 4-O-methyl gallic acid isolated from Syzygium myrtifolium leaves

“…The spectrum at δ 108.5 and 145.6 exhibits higher intensity peaks than the others, indicating two C for each peak. These data agree with previous reports on 4-O-methyl gallic acid ( Abhishek et al, 2019 , Farag et al, 2015 ).…”

“…Compared to gallic acid, 4-O-methyl gallic acid was less effective against distinct influenza strains ( Dao et al, 2019 ). In addition, 4-O-methyl gallic acid inhibits bacteria and yeast, particularly against Streptococcus faecalis , Cryptococcus neoformans ( Abhishek et al, 2019 ), and R. solanacearum ( Farag et al, 2015 ). Other investigations have also reported the efficacy of 4-O-methyl gallic acid in reducing the expression of AT1R and CD36 mRNA in Ang II-treated MDPs.…”

“…Active compounds that have been reported from Syzygium myrtifolium include anthocyanin, betulinic acid, dimethyl cardamonin, ursolic acid, (2S)-7-Hydroxy-5-methoxy-6,8-dimethyl flavanone, (S)-5,7-dihydroxy-6,8-dimethyl flavanone, (E)-2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone, (E)-2′,4′-dihydroxy-6′-methoxy chalcone ( Aisha et al, 2013 , Anggraini, 2017 , Memon et al, 2015 ). Avicularin was isolated from Euphorbia humifusa ( Ahn et al, 2019 ), Taxillus kaempferi ( Fujimori and Shibano, 2013 ), Myrcia tomentosa ( Da Silva Sa et al, 2017 ), Vaccinum vitis-idaea ( Riihinen et al, 2013 ), whereas 4-O-methyl gallic acid was isolated from Elaocarpus tonkinensis ( Dao et al, 2019 ), Phyllanthus polyphyllus ( Abhishek et al, 2019 ), Acacia arabica and Punica granatum ( Farag et al, 2015 ). Our study represents the initial documentation of the isolation of Avicularin and 4-O-methylgallic acid from the leaves of Syzygium myrtifolium .…”

Characterization, antibacterial, antioxidant, antidiabetic, and anti-inflammatory activities of green synthesized silver nanoparticles using Phragmanthera austroarabica A. G. Mill and J. A. Nyberg extract

“…Minimum inhibitory concentrations (μg/ml) of P. austroarabica extract and AgNPs obtained using agar plate diffusion assay are shown in Table 6 . Our results coincide with previous reports ( Xu and Lee, 2001 ; Cushnie and Lamb, 2005 ; Li et al, 2015 ; Jaisinghani, 2017 ; Abhishek et al, 2019 ; Marrez et al, 2019 ; Yang et al, 2020 ; Albutti et al, 2021 ; Nguyen and Bhattacharya, 2022 ; Qanash et al, 2022 ) that demonstrated the strong antimicrobial activity of either phenolics (namely gallic acid), flavonoids (in particular quercetin) or plant extract rich in these chemical constituents toward a number of microorganisms including P. vulgaris , P. aeruginosa , K. pneumoniae , and MRSA. These pathogens are well-documented eitological agents that were previously reported to be associated with hospital acquired infections ( Khan et al, 2015 ; Haque et al, 2018 ; Centers for Disease Control and Prevention (CDC), 2019 ).…”