Antimicrobial activity in methanolic extracts of several plant species from northern Argentina

Salvat, A; Antonacci, L.; Fortunato, Renée H.; Suarez, Enrique; Godoy, Héctor M.

doi:10.1078/0944-7113-00327

Cited by 70 publications

(54 citation statements)

References 4 publications

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“…testados, além disso, tem boa atividade antimicrobiana in vitro contra bactérias Gram-positivas, Escherichia coli e Pseudomonas aeruginosa 2 11 . Atividade antimicrobiana, inclusive contra micobactérias, tem sido demonstrada em plantas dos gêneros Jatropha (pinhão) 1 , Chenopodium (mastruz) 12 e Astronium (aroeira) 19 . Plantas do gênero Astronium (aroeira) também apresentam atividade antiinflamatória, sendo utilizadas na região contra tosse, bronquite, inflamação ovariana e úlceras externas 8 18 .…”

Section: Discussionunclassified

Sensibilidade antimicrobiana de bactérias aeróbicas isoladas de úlceras leishmanióticas, em Corte de Pedra, BA

Vera

Macedo

Ciuffo

et al. 2006

Rev. Soc. Bras. Med. Trop.

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A lesão cutânea ulcerada, manifestação clínica mais freqüente da leishmaniose tegumentar, geralmente localizada em membros inferiores, permanece ativa durante meses, expondo-se à colonização por microorganismos, componentes ou não da flora normal da pele. As condições de calor, umidade e má higiene, que acontecem freqüentemente em ambiente rural nas regiões tropicais, associadas à proximidade dessas úlceras com o solo, favorecem, sobremodo, a colonização por diversas bactérias 20 .Existem poucos relatos sobre a prevalência de bactérias em úlceras leishmanióticas. ABSTRACTA prospective study regarding aspects of antimicrobial susceptibility aspects was realized among patients with tegumentary leishmaniasis in Corte de Pedra, Bahia. Cases were composed mainly of adolescent and adult farmer patients with single lesions. Staphylococcus aureus predominated (83%) in the culteres with susceptibility to the majority of antibiotics. A mixed bacterial flora in ulcers was encountered in 37 (44,1%) patients. Among the Gram-negative bacteria isolated, Enterobacter sp (13.1%), Proteus sp (8.3%), Pseudomonas aeruginosa (7.1%) and Klebsiella sp (7.1%) were mainly found with susceptibility to ciprofloxacin, aminoglycosides, third generation cephalosporin and carbapenems.

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Section: Discussionunclassified

Sensibilidade antimicrobiana de bactérias aeróbicas isoladas de úlceras leishmanióticas, em Corte de Pedra, BA

Vera

Macedo

Ciuffo

et al. 2006

Rev. Soc. Bras. Med. Trop.

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“…É uma planta endêmica da caatinga, necessitando, como as outras citadas, de estratégias para conservação e manejo sustentável. A importância dessas espécies reside, principalmente, nas características da madeira (construção, lenha, carvão) e nas suas propriedades medicinais cientificamente comprovadas (antiinflamatória, cicatrizante e antimicrobiana) (MENEZES et al, 1988;CHAVES et al, 1998;VIANA et al, 2003;SALVAT et al, 2004).…”

Section: Introductionunclassified

Teor de taninos em três espécies medicinais arbóreas simpátricas da caatinga

et al. 2005

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RESUMO -O teor de taninos em três espécies medicinais do semi-árido do Nordeste do Brasil foi determinado. A partir de amostras das cascas do caule e folhas de 10 indivíduos de Anadenanthera colubrina (Vell.) Brenam, Myracrodruon urundeuva (Engl.) Fr. All. e Caesalpinia pyramidalis Tul., os teores de fenóis totais e taninos foram determinados em extratos metanólicos 80% pelo método de Folin-Ciocalteau, seguido do método da precipitação de proteínas. Adicionalmente, testou-se a hipótese de que a concentração de taninos está diretamente relacionada com a altura e diâmetro das plantas. As espécies estudadas apresentaram expressivos teores de extrativos tânicos, e os resultados não ratificaram a hipótese testada.Palavras-chave: Caatinga, taninos, Anadenanthera colubrina, Myracrodruon urundeuva e Caesalpinia pyramidalis. TANNIN CONCENTRATION IN THREE SIMPATRIC MEDICINAL PLANTS FROM CAATINGA VEGETATION INTRODUÇÃOTaninos são compostos secundários, presentes na maioria das plantas, que podem variar de concentração nos tecidos vegetais, dependendo da idade e tamanho da planta, da parte coletada, da época ou, ainda, do local de coleta (TEIXEIRA et al., 1990; SIMON et al.,1999;LARCHER, 2000). No Brasil, várias espécies são pesquisadas por suas propriedades tanantes; entre as principais estão Stryphnodendron adstringens (Martius) Coville, Dimorphandra mollis Benth., Anadenanthera colubrina (Vell.) Brenam, Acacia mearnssi De Wild, Psidium guajava L. e Myracrodruon urundeuva (Engl.) Fr.

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“…These bacteria and other aerobic bacteria directly invade wounds and interfere with the healing process via tissue damage, inflammation, fluid exudation and delay fibroplasia and collagen synthesis. [32] The plant extracts exhibited good antibacterial activity having MIC ranging from 4 to 128 mg/mL compared to 0.016 to 25 mg/mL for ciprofloxacin (Table 1) by the classification of Salvat et al [33]. The MIC value for ciprofloxacin against the test bacterial strains was much lower as compared to the extract due to the complexity of phytochemicals.…”

Section: Antibacterial Activity Of Pol Extractsmentioning

confidence: 99%

Antibacterial and ciprofloxacin modulating activity of Ptaeroxylon obliquum (Thunb.) Radlk leaf used by the Xhosa people of South Africa for the treatment of wound infections

Oyedemi

Falowo

et al. 2016

Biotechnology & Biotechnological Equipment

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The present work investigated the antibacterial activity of Ptaeroxylon obliquum leaves (POL) extracts in the presence or absence of ciprofloxacin by the broth microdilution method and timeÀkill assay against bacterial strains associated with wound infections. Free-radicalÀscavenging activity (FRSA) was determined using the stable 2,2-diphenyl-2-picrylhydrazyl hydrate (DPPH) bioassay method. The chemical composition of the most active antioxidant extract was analysed using a gas chromatograph interfaced with a mass spectrometer (GC-MS). All POL extracts showed good antibacterial activity against the bacterial strains, with a minimum inhibitory concentration (MIC) ranging from 4 to 128 mg/mL. The exposure of bacterial strains to POL extracts resulted in 2À64-fold reductions in the MIC of ciprofloxacin. Correspondingly, the timeÀkill curves showed that combined POL extracts and ciprofloxacin treatment inhibited bacterial growth below the lowest detectable limit after 24 h of incubation. Furthermore, the ethanol extract from P. obliquum (POE) had the highest total flavonoids content (TFC: 62.7 mg/quercetin equivalent/g), while the methanol extract of P. obliquum (POM) had the best total phenolic content (TPC: 275 mg/quercetin equivalent/g) and DPPH Ã -scavenging activity having 50% inhibitory concentration (IC 50 ) of 0.125 mg/mL. The chemical composition indicated the presence of aromatic and aliphatic compounds that are known to have a wide biological effect. The findings from this study suggest that POL extracts could be a source of pharmaceutical agents for treatment of skin diseases, wound infections and as putative candidates to modulate the multidrug resistance mechanism. KEYWORDSAntibacterial activity; modulation of resistance; Ptaeroxylon obliquum; timeÀkill kinetics; wound infection Abbreviations CFU colony-forming unit DPPH 2,2-diphenyl-2-picrylhydrazyl hydrate DMSO dimethyl suphuroxide FCR FolinÀCiocalteu reagent FRSA free-radicalÀscavenging activity GAE gallic acid equivalents GC-MS gas chromatographyÀmass spectrometry IC inhibitory concentration MHB MuellerÀHinton broth MIC minimum inhibitory concentration MTT 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide MW molecular weight POA Ptaeroxylum obliquum acetone POC Ptaeroxylum obliquum chloroform POL Ptaeroxylum obliquum leaf POM Ptaeroxylum obliquum methanol ROS reactive oxygen species SIC sub-inhibitory concentration TFC total flavonoids content TPC total phenolic content

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Antimicrobial activity in methanolic extracts of several plant species from northern Argentina

Cited by 70 publications

References 4 publications

Sensibilidade antimicrobiana de bactérias aeróbicas isoladas de úlceras leishmanióticas, em Corte de Pedra, BA

Sensibilidade antimicrobiana de bactérias aeróbicas isoladas de úlceras leishmanióticas, em Corte de Pedra, BA

Teor de taninos em três espécies medicinais arbóreas simpátricas da caatinga

Antibacterial and ciprofloxacin modulating activity of Ptaeroxylon obliquum (Thunb.) Radlk leaf used by the Xhosa people of South Africa for the treatment of wound infections

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