Antimicrobial activity from polymeric composites-based polydimethylsiloxane/TiO2/GO: evaluation of filler synthesis and surface morphology

Abstract

Antimicrobial substances may be used to reduce hospital infections and inhibit food contamination, thus ensuring the safety and well being of humans. The objective of this study was to evaluate the antimicrobial activity of the polymeric nanocomposites polydimethylsiloxane (PDMS) embedded with two types of fillers based on titanium dioxide (commercial TiO 2 P25 versus TiO 2 via facile Microwave-assisted hydrothermal-MAH synthesis) and graphene oxide (GO). The nanocomposites were prepared using different compositions, concentrations, and functionalizations (PDMS/TiO 2 /GO; PDMS/TiO 2 and PDMS/GO). The antimicrobial activity of the samples was evaluated for different treatments on Candida albicans, Staphylococcus aureus, and Enterococcus faecalis, by a modified direct contact test (mDCT). The samples were also evaluated on surface morphology and the roughness as a function of active particles insertion by atomic force microscopy (AFM). Most of the PDMS films whose polymer was embedded with GO and hydrothermal TiO 2 showed the highest inhibition growth of bacteria and Candida over 24 h. After 24 h, F, J, and H samples showed the best antibacterial activity, whereas E showed the best antifungal activity. The results indicated that the nanocomposites PDMS/GO/TiO 2 MAH and PDMS/GO sample enhanced antimicrobial activity in the treatments tested, therefore they were functional for contaminant reduction.

Injectable MMP-Responsive Nanotube-Modified Gelatin Hydrogel for Dental Infection Ablation

“…The direct contact test was performed to investigate the antimicrobial effects of the CHX-loaded nanotubemodified hydrogels in a planktonic model. 54 Samples (6 mm diameter × 2 mm thick) were disinfected by UV-irradiation and then placed on the wells of 96-well plates (n = 6/group). E. faecalis was grown overnight in BHI broth in aerobic conditions at 37 °C.…”

The use of decorated titanium oxide nanoparticles for the development of handmade textile heritage in Egyptian villages: Design, mechanical, flammability, and antibacterial properties

“…From these results, we conclude that a dramatic decline in bacterial growth was found with the raising of decorated TiO 2 ‐NPs ratio in the KF that showed the highest efficiency and activity against both type of bacteria by applying of higher concentration of nano‐TiO 2 (KF‐R/D‐0.6%). This result can be explained by the increase in the number of nanoparticles that embedded per unit area on the treated surface of the KF, thereby becoming very functioned by the R/D and TiO 2 NPs, thus maximizing the antibacterial effects 38,39 . Consequently, the obtained outcomes could open the path to produce novel interesting antibacterial KF fabrics for varying smart fabric technologies, thus conserving the cultural heritage.…”

“…This result can be explained by the increase in the number of nanoparticles that embedded per unit area on the treated surface of the KF, thereby becoming very functioned by the R/D and TiO 2 NPs, thus maximizing the antibacterial effects. 38,39 Consequently, the obtained outcomes could open the path to produce novel interesting antibacterial KF fabrics for varying smart fabric technologies, thus conserving the cultural heritage.…”

Cannabidiol-loaded microparticles embedded in a porous hydrogel matrix for biomedical applications

“…The direct contact test was performed to investigate the antimicrobial effect of the hydrogels in a planktonic model [ 36 , 37 ]. The hydrogels were tested against Staphylococcus aureus (ATCC 25923).…”