Antimicrobial Activity and Phytochemical Studies on Turkish Samples ofPapaver macrostomum.

Abstract

Three alkaloids, cheilantifoline, mecambrine, and laudanosine, and two flavonoids, luteoline and tricine, have been isolated from two samples of Papaver macrostomum Boiss. & Huet ex Boiss. (Papaveraceae) of Turkish origin. Antimicrobial tests have been performed on the extracts obtained from these species. It has been found that diethyl ether and acetone extracts of two samples obtained from the aerial parts of the plant have antimicrobial activity against almost all bacteria tested. The existence of flavonoids and the antimicrobial activity of this species are reported for the first time.

Papaver Plants: Current Insights on Phytochemical and Nutritional Composition Along with Biotechnological Applications

“…42 and 16 compounds were characterized, respectively, and a variation was observed depending on the color of the flowers [66]. P. macrostomum, which is widely distributed in Turkey, contains alkaloids such as protopine (protopine), benzylisoquinoline (macrostomine, dehydromacrostomine, sevanine), rhoeadine (rhoeadine, papaverrubine A-E), aporphine (iso-corydine), isopavine (amurensine, amurensinine), protoberberine (cheilantifoline), proaporphine (mecambrine), and benzyl tetrahydroisoquinoline (laudanosine) types [67]. Moreover, the major alkaloids of P. orientale were oripavine (morphinan type) and mecambridine (protoberberine type) and of P. pseudo-orientale were also mecambridine and isothebaine (aporphine type) and orientalidine (protoberberine type).…”

“…The methanol and aqueous extracts presented considerable amounts of the flavanol (−) -epicatechin and the benzoic acid syringic acid [ 76 ]. Moreover, the aerial parts of P. macrostomum had the flavone luteolin ( Figure 3 ) [ 67 ].…”