2009
DOI: 10.1089/jmf.2007.0000
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Antihyperglycemic Effects of Fruits of Privet (Ligustrum obtusifolium) in Streptozotocin-Induced Diabetic Rats Fed a High Fat Diet

Abstract: The protective effects of freeze-dried privet (Ligustrum obtusifolium) fruits (PFs) were observed in streptozotocin (STZ)-induced diabetic rats on a high fat diet by measuring levels of blood glucose, serum insulin, fructosamine, and hepatic reactive oxygen species generating and scavenging enzyme activities. A PF-supplemented diet was prepared by mixing an AIN-76 diet with powdered PF (final concentration, 1% or 2%). It was fed to STZ-induced diabetic rats on a high fat diet for 6 weeks. Diabetic animals rece… Show more

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Cited by 9 publications
(7 citation statements)
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“…Ligustrum ovalifolium L. is commonly called California privet or garden privet, is an ornamental semi-evergreen shrub original from East Asia, widely cultivated as ornamental plant. Ligustrum (privet) fruits are known to contain phenolic acids, flavonoids and triterpenoids, responsible for their antihyperglycemic, anticarcinogenic effect and immunomodulatory activity [ 3 , 19 , 20 , 21 ].…”
Section: Introductionmentioning
confidence: 99%
“…Ligustrum ovalifolium L. is commonly called California privet or garden privet, is an ornamental semi-evergreen shrub original from East Asia, widely cultivated as ornamental plant. Ligustrum (privet) fruits are known to contain phenolic acids, flavonoids and triterpenoids, responsible for their antihyperglycemic, anticarcinogenic effect and immunomodulatory activity [ 3 , 19 , 20 , 21 ].…”
Section: Introductionmentioning
confidence: 99%
“…Herbal medicine plays vital role as hypolipidemic (Yadav et al, 2008), abortifacient and contraceptive (Yakubu et al, 2010), antihypertensive (Nworgu et al, 2008), effective for treating skin diseases (Ajibesin et al, 2008), wound healers, and hypoglycemic effects and antimicrobial activities (Lee et al, 2009). Herbal medicine has numerous advantages such as low-cost, affordability, availability, accessibility, acceptability, and low toxicity; however, there are various disadvantages of consuming herbal products which include inappropriate formulations, lack of adequate scientific proof of the plant, imprecise diagnosis dosage and unstandardized usage which can lead to serious health risk to the patients (Elujoba et al, 2005).…”
Section: Introductionmentioning
confidence: 99%
“…[1] Today, medicinal plants are increasingly being used in most parts of the world as hypolipidemic,[2] contraceptive, abortifacients, emmenagogues, or oxytocic, antihypertensive,[3] treatment for skin diseases, wound healers, antimicrobial, and hypoglycemic. [4] Ethnobotanical information indicates that more than 800 plants are used as traditional remedies for the treatment of diabetes. [5] Hence, a large number of medicinal plants are available, it is very important to do the scientific validation of the drug to know their side effects in treatment.…”
Section: Introductionmentioning
confidence: 99%