Antihyperglycemic Activity of Aqueous Root Extract of<i>Rubia cordifolia</i>. in Streptozotocin-Induced Diabetic Rats

Baskar, R; Bhakshu, Lepakshi Md.; Bharathi, G. Vijaya; Reddy, S. Sreenivasa; Rasineni, Karuna; Reddy, G. Kesava; Desireddy, Saralakumari

doi:10.1080/13880200600798593

Cited by 30 publications

(20 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The levels of RBC, Hb, haematocrit, LUC and MCHC in the diabetic animals were drastically reduced which may be attributed to the infections on the normal body systems. This observation agrees with report of Baskar et al [17] who reported antihyperglycemic activity of aqueous root extract of Rubia cordifolia in streptozotocin-induced diabetic rats. The alterations of these parameters are well known to cause anaemic condition in man [18] .…”

Section: Discussionsupporting

confidence: 82%

Antidiabetic and haematological effect of aqueous extract of stem bark of Afzelia africana (Smith) on streptozotocin–induced diabetic Wistar rats

Aiyegoro

et al. 2011

Asian Pacific Journal of Tropical Biomedicine

103

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 82%

Antidiabetic and haematological effect of aqueous extract of stem bark of Afzelia africana (Smith) on streptozotocin–induced diabetic Wistar rats

Aiyegoro

et al. 2011

Asian Pacific Journal of Tropical Biomedicine

103

View full text Add to dashboard Cite

“…This was also observed by Baskar et al (2006) who reported antihyperglycemic activity of aqueous root extract of Rubia cordifolia in streptozotocin -induced diabetic rats. The alterations in these haematological parameters have also been reported in humans (Balasubraimanian et al, 2009).…”

Section: Discussionsupporting

confidence: 64%

Haematology and serum biochemistry of alloxan-induced diabetic rats administered with extracts of Phragmanthera incana (Schum.) Balle

Ogunmefun¹,

Fasola²,

Saba³

et al. 2017

Afr. J. Pharm. Pharmacol.

View full text Add to dashboard Cite

This study evaluated the toxic changes that may accompany treatment of diabetes with Phragmanthera incana, a mistletoe species growing on two plant hosts [Cola nitida (Kolanut; PICN) and Theobroma cacao (Cocoa; PITC)]. The toxic potential of this treatment regimen was evaluated using the effect of the extracts PICN and PITC on the haematology and serum chemistry of the diabetic rats. Alloxan-induced diabetic rats were treated with the extracts at doses of 200, 400 or 800 mg/kg or glibenclamide for 14 days. Blood samples were collected on day 15 for haematology and serum biochemistry. Haematological parameters analyzed were packed cell volume, haemoglobin, red blood cells, mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), white blood cell count, platelet count, lymphocytes, neutrophil, monocytes and eosinophil. Serum biochemical parameters analyzed were total protein, albumin, globulin, albuminglobulin ratio, aspartate transaminase, alanine transaminase, alanine phosphatase, blood urea nitrogen, creatinine, cholesterol, bilirubin and glucose. The results showed that P. incana extracts, regardless of the host plant decreased blood glucose and cholesterol levels. Although it depressed packed cell volume (PCV), it also alleviated other complications of diabetes such as liver and kidney injury, and may possess hepatoprotective effect.

show abstract

“…The extract of roots reduced the blood sugar level in alloxan treated diabetic rats, indicates that the extract has an extra pancreatic effect 24 . The aqueous root extracts was found to normalize hyperglycemia, hyper triglyceridemia, enhanced transaminases of liver and kidney, hypochromic microcytic anemia, and loss of body weight in streptozotocin -induced diabetic rat models 25 . Serum cholesterol and triglyceride level were decreased where as serum high density lipoprotein and protein levels were increased in diabetic rats 26 .…”

Section: Anti-diabetic:-mentioning

confidence: 99%

A Review Study of Medicinal Uses of Manjishtha (Rubia Cordifolia).

Singh¹,

Dadhich²,

Deepa³

2017

IJAR

View full text Add to dashboard Cite

Antihyperglycemic Activity of Aqueous Root Extract ofRubia cordifolia. in Streptozotocin-Induced Diabetic Rats

Cited by 30 publications

References 9 publications

Antidiabetic and haematological effect of aqueous extract of stem bark of Afzelia africana (Smith) on streptozotocin–induced diabetic Wistar rats

Antidiabetic and haematological effect of aqueous extract of stem bark of Afzelia africana (Smith) on streptozotocin–induced diabetic Wistar rats

Haematology and serum biochemistry of alloxan-induced diabetic rats administered with extracts of Phragmanthera incana (Schum.) Balle

A Review Study of Medicinal Uses of Manjishtha (Rubia Cordifolia).

Contact Info

Product

Resources

About