Antigen detection of Chlamydia trachomatis from the endocervix is not enough for screening of perinatal complications

Numazaki, Kei; Niida, Yuichi; Chiba, Shunzo

doi:10.1016/s0002-9378(97)70631-8

Cited by 7 publications

(5 citation statements)

References 2 publications

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“…Pneumonia due to C. trachomatis is a disease limited mainly to infants under 6 months of age [ 1,121. We reported four infants who developed neonatal C. tvachomatir infections and whose mothers had negative chlamydial EIAs during pregnancy [13].…”

Section: Discussionmentioning

confidence: 96%

“…Pneumonia due to C. trachomatis is a disease limited mainly to infants under 6 months of age [1,12]. We reported four infants who developed neonatal C. trachomatis infections and whose mothers had negative chlamydial EIAs during pregnancy [13]. Although transmission of the organism from mothers to their infants generally occurs at the time of delivery, with passage of the infant through the infected cervix, the possibility of intrauteine infection has been reported [1].…”

Section: Discussionmentioning

confidence: 99%

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Unclassified serovars of Chlamydia trachomatis isolated from Japanese infants

Numazaki

Ikehata

Chiba

et al. 1998

Clinical Microbiology and Infection

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Objective: To analyze antigenic and genetic variations of Chlamydia trachomatis among the serovars obtained from Japanese infants. Methods:The polymerase chain reaction (PCR) was used to amplify a large part of the major outer-membrane protein gene, and restriction fragment length polymorphism (RFLP) was used to identify the serovars of C. trachomatis from nasopharyngeal and conjunctival swabs from Japanese infants and neonates. Results:The typing of 10 nasopharyngeal isolates gave the following results: seven E, one H, and two unclassified serovars. The typing of seven conjunctival isolates gave the following results: five D, one F, and one unclassified serovar. Reactive patterns of these unclassified strains, determined by PCR-RFLP, to monoclonal antibodies were different from those of 15 reference serovars.Conclusions: Characterization of unclassified variants will allow more detailed epidemiologic studies of perinatal C. trachomatis infections i n Japan.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Unclassified serovars of Chlamydia trachomatis isolated from Japanese infants

Numazaki

Ikehata

Chiba

et al. 1998

Clinical Microbiology and Infection

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“…These tests are easily performed and less costly but have lower sensitivities than culture or PCR and have low positive predictive values in low prevalence populations such as Japan. [19]…”

Section: Discussionmentioning

confidence: 99%

Chlamydia trachomatisinfection in early neonatal period

Numazaki

Asanuma

Niida³

2003

BMC Infect Dis

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“…Recently, we reported cases of chlamydial infections in the early neonatal period. 15 Chlamydial antigen was not detected by enzyme inmmunoassay in any endocervical specimens. Although further studies in a large number of populations are definitely necessary, detection of serum IgG and IgA antibodies to C. trachomatis during late-stage pregnancy may allow clinicians to diagnose more perinatal chlamydial infections, and may be useful for the screening of infection.…”

Section: Discussionmentioning

confidence: 77%