Antifungal susceptibility, risk factors and treatment outcomes of patients with candidemia at a university hospital in Saudi Arabia

Abstract

Background: Candidemia is a major cause of morbidity and mortality in hospitalized patients. The spectrum of candidemia has been changed especially among critically ill patients due to emergence of non-albicans Candida (NAC) species. The increasing use of azole agents is suggested to be responsible for this epidemiological shift. NAC species are of special concern because of their high drug-resistance and increasing prevalence.The aim of this study was to detect antifungal-susceptibility patterns, treatment outcomes and associated risk factors in patients with candidemia who were admitted to King Abdulaziz University Hospital (KAUH), Jeddah, Kingdom of Saudi Arabia (KSA) .

Nosocomial Candiduria in Critically Ill Patients Admitted to Intensive Care Units in Menoufia University Hospitals, Egypt

“…Candidemia in ICUs is associated with a considerable increase in hospital costs and length of hospital stay [15]. Broad-spectrum antibiotics, a prolonged ICU stay for >20 days, the use of corticosteroids, diabetes and mucosal colonization with Candida, age < 1 year > 64 years, all are risk factors for invasive candidiasis [59].…”