Antifungal mechanism of bacillomycin D from Bacillus velezensis HN-2 against Colletotrichum gloeosporioides Penz

Antifungal Activity of Cyclic Tetrapeptide from Bacillus velezensis CE 100 against Plant Pathogen Colletotrichum gloeosporioides

“…Bacillus species demonstrating wide array of bioactive metabolites have been recognized as effective candidates to control several phytopathogens [14][15][16][42][43][44][45]. In this study, the BCF of B. velezensis CE 100 displayed significant antifungal activities against the pathogen, C. gloeosporioides, which causes anthracnose disease in plants.…”

“…The role of active metabolites derived from biocontrol agents as viable and reliable alternatives to chemical fungicides cannot be underestimated [9,[14][15][16][17]. Among various biocontrol agents, Bacillus species show strong abilities to restrict the growth of plant pathogens by synthesizing hydrolytic enzymes and antifungal compounds [14][15][16]18,19]. Moreover, Bacillus species are known to produce peptide antibiotics [20][21][22] used for biocontrol of agricultural crops [23].…”

“…These compounds can permeate and disrupt fungal cell membranes [26,27], thus reducing the likelihood of developing resistance compared to traditional antibiotics [28]. Bacillus velezensis also produce peptide antibiotics that can inhibit the growth of various fungi [16,22]. Its potential utility as a biocontrol agent against several fungal plant pathogens has recently been investigated [16,29,30].…”

“…Bacillus velezensis also produce peptide antibiotics that can inhibit the growth of various fungi [16,22]. Its potential utility as a biocontrol agent against several fungal plant pathogens has recently been investigated [16,29,30].…”

“…Numerous microorganisms have been used for controlling fungal diseases including the diseases caused by C. gloeosporioides [14][15][16]. However, many researchers are focusing on antagonistic microorganisms that can more effectively control C. gloeosporioides and improve crop production and quality.…”