Antifungal and antimycotoxigenic properties of chemically characterised essential oil of<i>Boswellia serrata</i>Roxb. ex Colebr.

Venkatesh, Hosur Narayanappa; Sudharshana, Tungeti Narasimhappa; Abhishek, Rayasandra Umesh; Thippeswamy, S.; Manjunath, K.; Mohana, Devihalli Chikkaiah

doi:10.1080/10942912.2017.1354882

Cited by 13 publications

(12 citation statements)

References 43 publications

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“…The biggest inhibition zone was observed for C. albicans as a consequence of Frankincense EO activity ( Table 1 , Figure 1 ). The antifungal activity of the essential oil extracted from Boswellia species, namely Frankincense EO, has already been reported by other research teams, who indicated that limonene was the component responsible for antifungal activity [ 56 , 57 ].…”

Section: Discussionmentioning

confidence: 71%

Activity of Liquid and Volatile Fractions of Essential Oils against Biofilm Formed by Selected Reference Strains on Polystyrene and Hydroxyapatite Surfaces

et al. 2021

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Biofilms are surface-attached, structured microbial communities displaying higher tolerance to antimicrobial agents in comparison to planktonic cells. An estimated 80% of all infections are thought to be biofilm-related. The drying pipeline of new antibiotics efficient against biofilm-forming pathogens urges the search for alternative routes of treatment. Essential Oils (EOs), extracted from medicinally important plants, are a reservoir of bioactive compounds that may serve as a foothold in investigating novel antibiofilm compounds. The aim of this study was to compare antimicrobial activity of liquid and volatile fractions of tested EOs against biofilm-forming pathogens using different techniques. In this research, we tested five EOs, extracted from Syzygium aromaticum L., Boswelia serrata Roxb., Juniperus virginiana L., Pelargonium graveolens L. and Melaleuca alternifolia Cheel., against planktonic and biofilm forms of five selected reference strains, namely Staphylococcus aureus, Enterococcus faecalis, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, and Candida albicans. To obtain cohesive results, we applied four various methodological approaches: to assess the activity of the liquid fraction of EOs, disc diffusion and the microdilution method were applied; to test EOs’ volatile fraction, the AntiBioVol assay and modified Antibiofilm Dressing Activity Measurement (A.D.A.M.) were used. The molecular composition and dynamics of antimicrobial substances released from specific EOs was measured using Gas Chromatography–Mass Spectrometry (GC-MS). The antimicrobial potency of EO’s volatile fraction against biofilm formed by tested strains differed from that of the liquid fraction and was related to the molecular weight of volatile compounds. The liquid fraction of CW-EO and volatile fraction of F-EO acted in the strongest manner against biofilm of C. albicans. The addition of 0.5% Tween 20 to liquid phase, enhanced activity of G-EO against E. coli and K. pneumoniae biofilm. EO activity depended on the microbial species it was applied against and the chosen assessment methodology. While all tested EOs have shown a certain level of antimicrobial and antibiofilm effect, our results indicate that the choice of EO to be applied against a specific biofilm-forming pathogen requires careful consideration with regard to the above-listed aspects. Nevertheless, the results presented in this research contribute to the growing body of evidence indicating the beneficial effects of EOs, which may be applied to fight biofilm-forming pathogens.

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Section: Discussionmentioning

confidence: 71%

Activity of Liquid and Volatile Fractions of Essential Oils against Biofilm Formed by Selected Reference Strains on Polystyrene and Hydroxyapatite Surfaces

et al. 2021

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“…Similarly, Morcia et al [15] observed lower ED 50 values of seven EOs were needed in the case of F. langsethiae when compared to effects on F. graminearum and F. sporotrichioides . However, most of these studies did not assess interactions with water availability which is critical for determining efficacy, especially in relation to toxin control [14,15,16,17,18,19,20,21,22]. It is also difficult to compare the dose-effect relationships obtained between species across the studies because different times and doses, and different matrices were used, often nutritionally unrelated to the commodity in which in situ control was required.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies have suggested that complete inhibition of FUMs could be achieved with 6 ppm of 3-carene, D-limonene and B-ocimene [21]. Also, ginger EOs inhibited FB 1 (2500 ppm), FB 2 (2000 ppm) and DON (2000 ppm) production [17,22].…”

Section: Discussionmentioning

confidence: 99%

“…In addition, F. verticillioides colonisation is more important in maize where it is primarily responsible for FUM contamination. Venkatesh et al [21] suggested that use of guggul EO at 10 ppm treatment of maize at 28 °C for 10 days reduced FUMs from 42.5 to 2.6 ppm; with complete inhibition of FB 1 achieved with 200 ppm of star anise or 50 ppb of allyl isothiocyanate [14,28]. Allyl isothiocyanate was found to inhibit the production of FB 1 by F. verticilloides [2,28].…”

Section: Discussionmentioning

confidence: 99%

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Influence of Two Garlic-Derived Compounds, Propyl Propane Thiosulfonate (PTS) and Propyl Propane Thiosulfinate (PTSO), on Growth and Mycotoxin Production by Fusarium Species In Vitro and in Stored Cereals

Mylona

García-Cela

Sulyok

et al. 2019

Toxins

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Two garlic-derived compounds, Propyl Propane Thiosulfonate (PTS) and Propyl Propane Thiosulfinate (PTSO), were examined for their efficacy against mycotoxigenic Fusarium species (F. graminearum, F. langsethiae, F. verticillioides). The objectives were to assess the inhibitory effect of these compounds on growth and mycotoxin production in vitro, and in situ in artificially inoculated wheat, oats and maize with one isolate of each respectively, at different water activity (aw) conditions when stored for up to 20 days at 25 °C. In vitro, 200 ppm of either PTS or PTSO reduced fungal growth by 50–100% and mycotoxin production by >90% depending on species, mycotoxin and aw conditions on milled wheat, oats and maize respectively. PTS was generally more effective than PTSO. Deoxynivalenol (DON) and zearalenone (ZEN) were decreased by 50% with 80 ppm PTSO. One-hundred ppm of PTS reduced DON and ZEN production in wheat stored at 0.93 aw for 20 days, although contamination was still above the legislative limits. Contrasting effects on T-2/HT-2 toxin contamination of oats was found depending on aw, with PTS stimulating production under marginal conditions (0.93 aw), but at 0.95 aw effective control was achieved with 100 ppm. Treatment of stored maize inoculated with F. verticilliodies resulted in a stimulation of total fumonsins in most treatments. The potential use of such compounds for mycotoxin control in stored commodities is discussed.

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“…Furthermore, the clinical investigation of B. serrata extract found to be providing significant improvement in patients suffering from osteoarthritis. [ 111 ] The animal study declared the usage of n‐hexane extract of gum resin of B. serrate in combination with methanolic extract of rhizome of Glycyrrhiza glabra tends to be exhibiting a potent anti‐arthritic activity in male Wistar rats and preventing migration of leucocytes and hence acting as antirheumatoid therapy. [ 112 ] Cannabis sativum – The oil extracted from seeds of cannabis sativum belonging to family Urticaceae is used as anti‐inflammatory in rheumatism and seen to be highly effective in reduction of pain and inflammation.…”

Section: The Various Herbal Plants Used In the Treatment Of Rheumatoimentioning

confidence: 99%

Medicinal plants used against various inflammatory biomarkers for the management of rheumatoid arthritis

Singh

Mahajan

et al. 2020

Journal of Pharmacy and Pharmacology

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Objectives Rheumatoid arthritis is a chronic autoimmune disease manifested clinically by polyarthralgia associated with joint dysfunction triggering the antibodies targeting against the self‐neoepitopes determined by autoimmune responses associated with chronic arthritic attacks. The activation of macrophages and other defence cells in response to self‐epitopes as biomarkers in RA provides a better understanding of pathogenesis of disease and has led to the development of novel therapeutic approaches acting as potent inhibitors of these cells. Key findings The current review retrieved the various medicinal plants possessing an active phytoconstituents with anti‐inflammatory and antioxidant properties, which tends to be effective alternative approach over the synthetic drugs concerned with high toxic effects. The current available literature provided an evident data concluding that the active constituents like fatty acids, flavonoids, terpenes and sesquiterpene lactones attenuate the RA symptoms by targeting the inflammatory biomarkers involved in the pathogenesis of RA. Summary Despite the various synthetic treatment approaches targeting immune cells, cytokines improved the quality of life but still the drug management is challenging due to toxic and chronic teratogenic effects with anti‐arthritic drugs. The current review has elaborated the selected traditionally used herbal medicinal plants with phytoconstituents possessing anti‐inflammatory activity by suppressing the inflammatory biomarkers with lesser side effects and providing the future exploration of natural drug therapy for rheumatoid arthritis.

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Antifungal and antimycotoxigenic properties of chemically characterised essential oil ofBoswellia serrataRoxb. ex Colebr.

Cited by 13 publications

References 43 publications

Activity of Liquid and Volatile Fractions of Essential Oils against Biofilm Formed by Selected Reference Strains on Polystyrene and Hydroxyapatite Surfaces

Activity of Liquid and Volatile Fractions of Essential Oils against Biofilm Formed by Selected Reference Strains on Polystyrene and Hydroxyapatite Surfaces

Influence of Two Garlic-Derived Compounds, Propyl Propane Thiosulfonate (PTS) and Propyl Propane Thiosulfinate (PTSO), on Growth and Mycotoxin Production by Fusarium Species In Vitro and in Stored Cereals

Medicinal plants used against various inflammatory biomarkers for the management of rheumatoid arthritis

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