Antifungal and Antibacterial Activities of Juice and Ethanolic Extracts of Garcinia Mangostana L. Leaves

Abstract

Objective: Garcinia mangostana is a plant that can be used as a traditional medicine to treat various infectious diseases for the treatment of diarrhea, skin infection, and chronic wounds. The activity as antifungal and antibacterial of juice and ethanolic extract from G. mangostana leaves were investigated.
 Methods: Juice and ethanolic extract were concentrated using a rotary evaporator to get concentrated extract with rendemen 2.571 and 5.647% (w/w). Juice and ethanolic extract dilution method were employed to evaluate the antifungal activity against Saccharomyces cerevisiae. Ethanolic extract dilution method was used to assess the antibacterial activity against Bacillus subtilis and Escherichia coli.
 Results: The results of this research showed that juice and ethanolic extract were effective against S. cerevisiae, and the minimum inhibitory concentration was 1000, and 500 mg/mL. Antibacterial activity of the G. mangostana leaves ethanolic extract showed that the action was potential with the inhibition zone in B. subtilis and E. coli. 
 Conclusions: The conclusion of this study is that juice and ethanolic extract of G. mangostana leaves have possible antifungal and antibacterial activity.

Impact of different drying methods on nutritional quality of Garcinia cowa and Garcinia pedunculata fruits

“…Traditional use of G. cambogia fruit pericarp extracts in multiple traditional medicinal system to treat bacterial diseases and cancer was validated by Hart and Cock (2016). The juice and ethanolic extract of G. mangostana leaves have possible antifungal and antibacterial activity (Diniatik et al, 2019) whereas the fruit rind of G. indica has significant antidepressant and anxiolytic effect (Dhamija et al, 2017). The main component of fruit rind is garcinol, isogarcinol and camboginol.…”

Designing and Quality Aspects of Aseptic Process Simulation

“…Selecting suitable growth media [4] Demonstration of nutrient growth promotion properties Environmental monitoring Formulation of bulk media solution [5] Microbial performance and bio-burden examination Sterilization of the media using suitable sterilization techniques Filling of media into containers Filled vials must be incubated and evaluated…”

“…A standard check is the location of settle plates on the rear of the filling machine where there is little or no operator involved. Routine particle tracking is useful for the rapid identification of major air cleanliness deviations from eligible processing requirements (e. g. destination of clean areas) [5,9]. The particulate monitoring involves the monitoring of the non-viable and viable particles which come under environmental monitoring.…”

“…The efficacy of the disinfectants and procedures should be evaluated in terms of their ability to ensure that possible contaminants are extracted from surfaces sufficiently [15]. To avoid contamination, disinfectants must be sterile, properly maintained in suitable containers and not used for longer than the duration specified in the written protocol [5,9].…”