2014
DOI: 10.1590/s1517-83822014000200024
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Abstract: Fungal infections have become a major problem of worldwide concern. Yeasts belonging to the Candida genus and the pathogenic fungus Cryptococcus neoformans are responsible for different clinical manifestations, especially in immunocompromised patients. Antifungal therapies are currently based on a few chemotherapeutic agents that have problems related to effectiveness and resistance profiles. Microemulsions are isotropic, thermodynamically stable transparent systems of oil, water and surfactant that can improv… Show more

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Cited by 21 publications
(11 citation statements)
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“…Additionally, w/o µEs are particularly interesting for oral protein delivery due to their increased oral bioavailability through the gastrointestinal tract and their protection capacity [ 144 ]. A large number of drugs, such as antibiotics [ 141 , 142 , 143 , 144 , 145 , 146 ], antifungals [ 147 , 148 , 149 ], anti-inflammatory [ 150 , 151 , 152 , 153 , 154 ] and immunosuppressive [ 155 ] molecules have been used in μEs systems.…”
Section: Achievements and Challengesmentioning
confidence: 99%
“…Additionally, w/o µEs are particularly interesting for oral protein delivery due to their increased oral bioavailability through the gastrointestinal tract and their protection capacity [ 144 ]. A large number of drugs, such as antibiotics [ 141 , 142 , 143 , 144 , 145 , 146 ], antifungals [ 147 , 148 , 149 ], anti-inflammatory [ 150 , 151 , 152 , 153 , 154 ] and immunosuppressive [ 155 ] molecules have been used in μEs systems.…”
Section: Achievements and Challengesmentioning
confidence: 99%
“…After being equilibrated, the mixtures were assessed visually and determined as a microemulsion or coarse emulsions. The phase diagram constructed using PROSIM software 4, [14][15][16] .…”
Section: Construction Of Pseudo-ternary Phase Diagramsmentioning
confidence: 99%
“…The prepared microemulsion diluted with Water with proper dilution. After ensuring complete dispersion of the formulation the droplet size of resultant ME was determined by photon correlation spectroscopy that analyzes the fluctuation in light scattering due to the Brownian motion of the droplets as a function of time using a DLS spectrophotometer (Model DLS700, Malvern Electronics Company Ltd., Japan).The average diameter (Z-AVE) and polydispersity index (PDI) of ME were determined by using a Malvern (Model DLS700, Malvern Electronics Company Ltd., Japan) at a fixed angle of 90˚ and at 25˚C 14,15,17 .…”
Section: Droplet Size Analysismentioning
confidence: 99%
“…The clear zone formed surrounding each disc if observed and taken as the minimal inhibitory concentration of the curcumin oil. [10,11] …”
Section: Susceptibility Testmentioning
confidence: 99%