Antifungal activities of Cunninghamia lanceolata heartwood extractives

Wang, Jing; Li, Jian; Li, Shujun; Freitag, Camille; Morrell, Jeffrey J.

doi:10.15376/biores.6.1.606-614

Cited by 64 publications

(15 citation statements)

References 4 publications

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“…Cedrol was reported to be one of the most termicidal components isolated from CWO (McDaniel et al, 1989 ; McDaniel and Dunn 1994 ) and cedrol alone was repellent to both red imported fire ants and little fire ants (Eller et al 2014 , 2015 ). Mun and Prewitt ( 2011 ) and Wang et al ( 2011 ) both reported cedrol as one of the most active antifungal (wood-decay) components in extracts from J. virginiana and Cunninghamia lanceolata , respectively. Although cedrol is the most abundant component of the CO 2 -derived CWO and possibly the most active component as well, unfractionated CWO might be the most cost-effective material to use.…”

Section: Discussionmentioning

confidence: 99%

Repellency and toxicity of a CO2-derived cedarwood oil on hard tick species (Ixodidae)

et al. 2022

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The repellency and toxicity of a CO2-derived cedarwood oil (CWO) was evaluated against actively questing unfed nymphs of four species of hard ticks: Amblyomma americanum (L.), Dermacentor variabilis (Say), Ixodes scapularis Say, and Rhipicephalus sanguineus (Latreille). Using a vertical climb bioassay for repellency, nymphs of these species avoided a CWO-treated filter paper in proportional responses to treatment concentrations. At 60 min of exposure, I. scapularis nymphs were most sensitive with 50% repellency concentration (RC50) of 19.8 µg cm−2, compared with RC50 of 30.8, 83.8 and 89.6 µg cm−2 for R. sanguineus, D. variabilis and A. americanum, respectively. Bioassays determined the lethal concentration for 50% (LC50) and 90% (LC90) mortality of nymphs exposed to CWO in treated vials after 24- and 48-h exposure. After 24 h exposure, the LC50 values were 1.25, 3.45 and 1.42 µg cm−2 and LC90 values were 2.39, 7.59 and 4.14 µg cm−2 for D. variabilis, I. scapularis and R. sanguineus, respectively, but had minimal effect on A. americanum. After 48 h exposure, the LC50 values were 4.14, 0.78, 0.79 and 0.52 µg cm−2, and LC90 values were 8.06, 1.48, 1.54 and 1.22 µg cm−2 for A. americanum, D. variabilis, I. scapularis and R. sanguineus, respectively. The repellency of CWO on tick species decreased with time. The repellency and toxicity bioassays demonstrated concentration-dependent responses of tick nymphs to the oil, indicating the potential of the CO2-derived cedarwood oil be developed as an eco-friendly repellent and/or acaricide.

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Section: Discussionmentioning

confidence: 99%

Repellency and toxicity of a CO2-derived cedarwood oil on hard tick species (Ixodidae)

et al. 2022

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“…Many plants emit eudesma-4,11-diene (1) as a minor component of biologically active VOCs mixtures or essential oils (Yoshida et al, 1967;Chu et al, 2011, Lee andVairappan, 2011;Takahashi et al, 2011, Wang et al, 2011. While 1 is produced by some basidiomycete and ascomycete fungi and by some actinomycetes, no biological activity has been described for either fungi or bacteria (Rösecke et al, 2000;Ayoub et al, 2009, Brock andRabe et al, 2013, Yuan et al, 2013.…”

Section: Discussionmentioning

confidence: 99%

Volatile Molecules Secreted by the Wheat Pathogen Parastagonospora nodorum Are Involved in Development and Phytotoxicity

et al. 2020

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Septoria nodorum blotch is a major disease of wheat caused by the fungus Parastagonospora nodorum. Recent studies have demonstrated that secondary metabolites, including polyketides and non-ribosomal peptides, produced by the pathogen play important roles in disease and development. However, there is currently no knowledge on the composition or biological activity of the volatile organic compounds (VOCs) secreted by P. nodorum. To address this, we undertook a series of growth and phytotoxicity assays and demonstrated that P. nodorum VOCs inhibited bacterial growth, were phytotoxic and suppressed self-growth. Mass spectrometry analysis revealed that 3-methyl-1-butanol, 2-methyl-1-butanol, 2-methyl-1-propanol, and 2phenylethanol were dominant in the VOC mixture and phenotypic assays using these short chain alcohols confirmed that they were phytotoxic. Further analysis of the VOCs also identified the presence of multiple sesquiterpenes of which four were identified via mass spectrometry and nuclear magnetic resonance as β-elemene, α-cyperone, eudesma-4,11-diene and acora-4,9-diene. Subsequent reverse genetics studies were able to link these molecules to corresponding sesquiterpene synthases in the P. nodorum genome. However, despite extensive testing, these molecules were not involved in either of the growth inhibition or phytotoxicity phenotypes previously observed. Plant assays using mutants of the pathogen lacking the synthetic genes revealed that the identified sesquiterpenes were not required for disease formation on wheat leaves. Collectively, these data have significantly extended our knowledge of the VOCs in fungi and provided the basis for further dissecting the roles of sesquiterpenes in plant disease.

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“…Accordingly, the BO was more active than CWO against the white-rot decay fungi. Cedrol, a major component of CWO and a sesquiterpene alcohol, has previously been reported to have anti-termitic activity (McDaniel et al 1989) and antifungal activity (Chang et al 1999;Cheng et al 2011;Mun and Prewitt 2011;Wang et al 2011). The sesquiterpenes in CWO have also been reported to be responsible for the antifungal activity of CWO and BO against brown-rot fungi (Bauch et al 2004;Mun and Prewitt 2011).…”

Section: Introductionmentioning

confidence: 99%

“…The plant family Cupressaceae, in particular, has several examples of active essential oils or extracts with anti-termitic activity (French et al 1979;Chang et al 2001), antifungal activity (Morita et al 1997;Cheng et al 2005;Wu et al 2005;Wan et al 2007;Wang et al 2011), or both (Chang et al 2003;Taylor et al 2006). In addition, sesquiterpenes from Cupressaceae have been identified to have both anti-termitic (Watanabe et al 2005;Mankowski et al 2016;Hassan et al 2017) and antifungal activities (Bauch et al 2004;Cheng et al 2005).…”

Section: Introductionmentioning

confidence: 99%

Effects of loblolly pine extract, primary and quaternary alkyl ammonium chlorides combined with burgundy oil from eastern red cedar against subterranean termites and wood-decay fungi

Eller

Mankowski

Kirker

et al. 2020

BioRes

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Burgundy oil (BO) from Eastern red cedar provides resistance against termites and wood-decay fungi and is enhanced when combined with an amylose inclusion complex (AIC) containing hexadecylammonium chloride (HAC). Indirect evidence also indicated that a methanol Loblolly pine extract (LPE) was inhibitory against termites. This study compared the effects of HAC and didecyldimethylammonium chloride (DDAC) combined with LPE and BO on termites and wood-decay fungi. Southern pine was treated by vacuum/pressure impregnation and resistance evaluated after exposure to termites and decay fungi. The combination of BO and either HAC/AIC or DDAC/AIC reduced wood mass losses by termites, increased termite mortality, and inhibited all wood-decay fungi. The HAC/AIC and DDAC/AIC resulted in equivalent mass losses by termites and termite mortalities. The DDAC was slightly more inhibitory than the HAC against wood-decay fungi. Given the slight advantage of DDAC over HAC and because DDAC is currently used to preserve wood, DDAC might be preferred over HAC. The LPE had a very minor effect on mass loss by termites, termite mortality, and only a slight inhibitory effect on G. trabeum and T. versicolor, while R. placenta and I. lacteus were unaffected. Higher concentrations of DDAC and/or LPE might improve protection against termites and wood-decay fungi.

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Antifungal activities of Cunninghamia lanceolata heartwood extractives

Cited by 64 publications

References 4 publications

Repellency and toxicity of a CO2-derived cedarwood oil on hard tick species (Ixodidae)

Repellency and toxicity of a CO2-derived cedarwood oil on hard tick species (Ixodidae)

Volatile Molecules Secreted by the Wheat Pathogen Parastagonospora nodorum Are Involved in Development and Phytotoxicity

Effects of loblolly pine extract, primary and quaternary alkyl ammonium chlorides combined with burgundy oil from eastern red cedar against subterranean termites and wood-decay fungi

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