Antifouling activities of anti-histamine compounds against the barnacle Amphibalanus (=Balanus) amphitrite

Jin, Cuili; Miao, Li; Feng, Ke; Zhou, Xiaojian

doi:10.1016/j.jembe.2013.12.006

Cited by 10 publications

(12 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…for the evaluation of toxic effects because of exposure to the antihistamine PM. Another study in the literature 15 showed that no lethal effect has been observed for tested concentrations of PM (2.5−20 μg/mL) on another crustacean species (Amphibalanus amphitrite). The authors have demonstrated that larvae were alive and able to move without disturbance during the entire periods of experiments (24−96 h) for all the concentrations tested.…”

Section: ■ Discussionmentioning

confidence: 99%

“…Antihistamines are a class of pharmaceutical products widely used, whose active ingredients or metabolites are globally widespread in influent, effluent, and surface waters, particularly in Europe and North America . As regards aquatic organisms, active pharmaceutical ingredients pose an alarming risk to nontarget aquatic organisms, as many taxa have evolutionarily conserved molecular drug targets similar to humans. − Some studies have evaluated the toxicity of antihistamines on model organisms such as Daphnia magna and Amphibalanus Amphitrite . These studies show that the test performed on D.…”

Section: Introductionmentioning

confidence: 99%

“… 11 − 13 Some studies have evaluated the toxicity of antihistamines on model organisms such as Daphnia magna ( 14 ) and Amphibalanus Amphitrite . 15 These studies show that the test performed on D. magna can detect toxicity effects at low concentrations, while the studies on Amphibalanus amphitrite have evaluated the possible use of antihistamines as products for antifouling, as some nontoxic concentrations would still allow the larvae to metamorphose in the adult stage. Artemia sp.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Acute Toxicity of a Marine Emerging Pollutant (Promethazine Hydrochloride) on Artemia sp

et al. 2022

View full text Add to dashboard Cite

Recently, there has been a worrying increase in the pollution of the aquatic ecosystem caused by emerging contaminants (ECs) detected in wastewater effluent discharges. Although traces of ECs in waters have been found in low concentrations, it leads to negative effects for nontarget organisms. Antihistamines are a class of drugs largely used, whose metabolites are widespread in the aquatic ecosystem. The aim of the study was to evaluate the short-term effects of promethazine hydrochloride on nauplii of Artemia sp. A high percentage of mortality and morphological alterations were found. The results suggest a possible correlation between exposure to antihistamine and an acceleration of larval development.

show abstract

Section: ■ Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Acute Toxicity of a Marine Emerging Pollutant (Promethazine Hydrochloride) on Artemia sp

et al. 2022

View full text Add to dashboard Cite

show abstract

“…In addition, the synthetic poly-APS analog APS8 can compete with acetylcholine at the cholinergic receptors, blocking cholinergic neural signals and inducing the hormetic response of barnacle cyprids [ 33 ]. Furthermore, histamine neurotransmitter signaling is closely involved in the regulation of the settlement process because histamine receptor antagonists (e.g., triprolidine and cetirizine) can effectively inhibit the attachment and metamorphosis of barnacle cyprids [ 34 , 35 , 36 ].…”

Section: Antifouling Compounds With Proposed Specific Targetsmentioning

confidence: 99%

Review on Molecular Mechanisms of Antifouling Compounds: An Update since 2012

Chen

Qian

2017

Marine Drugs

View full text Add to dashboard Cite

Better understanding of the mechanisms of antifouling compounds is recognized to be of high value in establishing sensitive biomarkers, allowing the targeted optimization of antifouling compounds and guaranteeing environmental safety. Despite vigorous efforts to find new antifouling compounds, information about the mechanisms of antifouling is still scarce. This review summarizes the progress into understanding the molecular mechanisms underlying antifouling activity since 2012. Non-toxic mechanisms aimed at specific targets, including inhibitors of transmembrane transport, quorum sensing inhibitors, neurotransmission blockers, adhesive production/release inhibitors and enzyme/protein inhibitors, are put forward for natural antifouling products or shelf-stable chemicals. Several molecular targets show good potential for use as biomarkers in future mechanistic screening, such as acetylcholine esterase for neurotransmission, phenoloxidase/tyrosinase for the formation of adhesive plaques, N-acyl homoserine lactone for quorum sensing and intracellular Ca2+ levels as second messenger. The studies on overall responses to challenges by antifoulants can be categorized as general targets, including protein expression/metabolic activity regulators, oxidative stress inducers, neurotransmission blockers, surface modifiers, biofilm inhibitors, adhesive production/release inhibitors and toxic killing. Given the current situation and the knowledge gaps regarding the development of alternative antifoulants, a basic workflow is proposed that covers the indispensable steps, including preliminary mechanism- or bioassay-guided screening, evaluation of environmental risks, field antifouling performance, clarification of antifouling mechanisms and the establishment of sensitive biomarkers, which are combined to construct a positive feedback loop.

show abstract

“…In addition, ship consume additional fuel due to the increased weight and the greater drag effect [16,17]. Increasing fuel consumption exacerbates CO 2 emissions and incurs higher costs [18]. Therefore, to offset the economic threat, biofouling management and control are critical.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Recruitment Patterns of Sessile Marine Invertebrates According to Substrate Characteristics

Bae

Ubagan

Shin

et al. 2022

IJERPH

View full text Add to dashboard Cite

A community of benthic invertebrates, including sessile adult-stage invertebrates, can negatively effect corrosion, deformation, and increased fuel consumption by attaching to artificial structures, a phenomenon known as marine biofouling. Investigating the relationship between benthic communities and artificial structures or substrates (to which the organisms attach) can help clarify the factors influencing marine biofouling. Therefore, in our study, natural (stone) and artificial (rubber, tarpaulin, and iron) substrates were installed in three harbors (Mokpo, Tongyeong, and Busan), and the structures of the communities attached to each substrate were compared. The total study period was 15 months (September 2016 to December 2017), and field surveys were performed at 3-month intervals. The three survey sites had significant differences in the structure of the sessile community present. In particular, Tongyeong was significantly different from Mokpo and Busan due to the continuous dominance of Cirripedia. When comparing natural and artificial substrate by sites, significant differences were observed in the community structure in all three surveyed sites. In Mokpo and Busan, colonial ascidians were dominant on natural substrate rather than artificial substrates; post-summer, Cirripedia coverage was higher on artificial substrates than natural substrate due to corrosion. Tongyeong showed a different pattern from that of Mokpo and Busan. After the summer, Bivalvia dominated on natural substrate over artificial substrates, affecting the differences between natural and artificial substrates. Our results demonstrate the recruitment patterns of sessile marine invertebrates according to substrate characteristics and can be used as basic information for biofouling management in marine environment.

show abstract

Antifouling activities of anti-histamine compounds against the barnacle Amphibalanus (=Balanus) amphitrite

Cited by 10 publications

References 32 publications

Acute Toxicity of a Marine Emerging Pollutant (Promethazine Hydrochloride) on Artemia sp

Acute Toxicity of a Marine Emerging Pollutant (Promethazine Hydrochloride) on Artemia sp

Review on Molecular Mechanisms of Antifouling Compounds: An Update since 2012

Comparison of Recruitment Patterns of Sessile Marine Invertebrates According to Substrate Characteristics

Contact Info

Product

Resources

About