2005
DOI: 10.1016/j.jep.2005.04.006
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Antidiarrhoeal activity of the methanol extract of the barks of Xylocarpus moluccensis in castor oil- and magnesium sulphate-induced diarrhoea models in mice

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Cited by 86 publications
(45 citation statements)
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“…Magnesium sulphate causes increased loss of intestinal content due to the reduction in reabsorption of water and cholecystokinin release from the duodenal mucosa. These increase the secretion and motility of small intestine, prevent the reabsorption of sodium chloride and water, and induce diarrhea (Gálvez et al, 1993;Uddin et al, 2005). In this study, the extracts showed a dose-dependent reduction in fecal droppings in both castor oil-and magnesium sulphate-induced diarrhea (Table 2).…”
Section: Discussionmentioning
confidence: 53%
See 1 more Smart Citation
“…Magnesium sulphate causes increased loss of intestinal content due to the reduction in reabsorption of water and cholecystokinin release from the duodenal mucosa. These increase the secretion and motility of small intestine, prevent the reabsorption of sodium chloride and water, and induce diarrhea (Gálvez et al, 1993;Uddin et al, 2005). In this study, the extracts showed a dose-dependent reduction in fecal droppings in both castor oil-and magnesium sulphate-induced diarrhea (Table 2).…”
Section: Discussionmentioning
confidence: 53%
“…after 30 min of the administration of the vehicle, drug or extracts. After observing the diarrheal droppings for the next 4 h, the percent (%) inhibition of defecation was calculated (Uddin et al, 2005).…”
Section: Antidiarrheal Activity Test In Magnesium Sulphate-induced DImentioning
confidence: 99%
“…In continuation of our phytochemical and pharmacological screening of Bangladeshi medicinal plants (Uddin et al, 2005(Uddin et al, , 2007aSaha et al, 2007;Datta et al, 2007), we now report on the antidiarrhoeal property of Anthocephalus cadamba fl owering tops.…”
Section: Introductionmentioning
confidence: 82%
“…Castor oil-induced diarrhea was done according to the method of Soba et al [8] and Uddin et al [9] . Rats of either sex were divided into four groups of five rats each.…”
Section: Ethical Clearancementioning
confidence: 99%