Antidiabetic Potential of the Oyster Mushroom Pleurotus Florida (Mont.) Singer

Abstract

Objective: The present investigation comprises, in vitro antidiabetic activity such as α-amylase and α-glucosidase inhibitory activities and in vivo antidiabetic activity of methanolic extract of Pleurotus florida. Methods:The fruiting bodies of Pleurotus florida were obtained from Mushroom Unit, Department of Biology, Gandhigram Rural Institute-Deemed University, Gandhigram, Dindigul, Tamil Nadu, India. Sample preparation, qualitative phytochemical analysis, in vitro antidiabetic activities namely α-amylase and α-glucosidase inhibitory activity and in vivo antidiabetic activity namely evaluation of alloxan induced diabetic rats were carried out following the methods reported previously. Results:In vitro and in vivo antidiabetic activity of P. florida exhibited significant results for its α-amylase (94.93±1.75 % at 1000 µg/ml) and α-glucosidase inhibitory activity (84.90±0.42 % at 1000 µg/ml) in a dose-dependent manner. The extract also showed significant antidiabetic activity on in vivo (p<0.05) at the tested dose level (200 mg/kg b. w) this was comparable to Glibenclamide, a standard antidiabetic drug. Conclusion:The presence of phytochemicals namely phenols, flavonoids, saponins, tannins and terpenoids may be responsible for such antidiabetic activity. These results reveal that P. florida can be used as a potential antidiabetic agent.

Growing (Pleurotus Pulmonarius) on Various Local Substrates in the Kurdistan Region of Iraq

“…Phytochemicals such as phenols, flavonoids, saponins, tannins, and terpenoids may be responsible for the antidiabetic effects of the substance. Comes about uncover that Pleurotus pulmonarius can be utilized as a potential antidiabetic specialist, utilized as an effectively available source of common antidiabetic and as a conceivable food supplement or within the pharmaceutical industry [9] Oyster mushroom could be a kind of saprophyte organism that lives on softwoods and obtains food by utilizing the remainders of organic matter. Oyster mushrooms, counting mushrooms that do not have chlorophyll (does not have leaf green ingredients) so they cannot prepare food by themselves.…”