Antidiabetic potential of mangrove plants: a review

Abstract

Diabetes mellitus is a heterogeneous group of metabolic disorders characterized by persistent hyperglycaemia and becoming a serious threat to mankind health in all parts of the world. Production of reactive oxygen species and disturbed capacity of antioxidant defence have been reported for enhanced production of free radicals in diabetic subjects. As oxidative stress is found to be a central event in the development of diabetic complications, hence antioxidants may play an important role in the improvement of diabetes and its associated complications. Currently there has been an increased interest globally to identify antioxidant compounds that are pharmacologically potent and have low or no side effects. Phytochemicals and metabolites from mangrove plants are reported to exhibit strong antioxidant properties in terms of both enzymatic and non-enzymatic activities. Recent researches have also revealed that a number of mangrove plants have shown antidiabetic activities attributed to their unique metabolites such as flavonoids, triterpenoids, limonoids and polysaccharides. Thus, mangrove plants can be of great use in tackling diabetic and its associated oxidative stress mediated complications. The present review highlights a relation between oxidative stress and diabetes and the role of mangrove plants in alleviating diabetes, in general, and oxidative stress mediated diabetic complications, in particular.

The genusAvicennia, a pioneer group of dominant mangrove plant species with potential medicinal values: a review

“…The available literatures have reported that most of the Avicennia species have been traditionally used as a medicine for a wide array of diseases worldwide by the local communities inhabiting the mangrove forests (Bandaranayake 2002, Das et al 2016. From many of the ethnomedicinal uses of the genus, the widest applications have been in the treatment of rheumatism, pregnancy, ulcer and smallpox (Bandaranayake 2002).…”

Influence of reactors, microbial carbohydrate uptake, and metabolic pathways on ethanol production from grass biomass: A review

“…Following it, the optimized sugar sources (glucose and xylose) along with bark extracts of X granatum with different concentrations (1, 3, and 5 mg/10 mL of sugar solution) were utilized for the growth of the three organisms over an incubation period from 0 to 72 hours. The ethanol bark extracts of X. granatum have been reported earlier for its potential to increase glucose uptake in yeast cell during the assessment of antidiabetic activity . The reason for such activity may be attributed to the fact that X. granatum plant being rich in polyphenols has prominent free radical scavenging potential that might play an important role in protecting yeast cells from osmotic stress allowing them to have prolonged growth period.…”

“…The ethanol bark extracts of X. granatum have been reported earlier for its potential to increase glucose uptake in yeast cell during the assessment of antidiabetic activity . The reason for such activity may be attributed to the fact that X. granatum plant being rich in polyphenols has prominent free radical scavenging potential that might play an important role in protecting yeast cells from osmotic stress allowing them to have prolonged growth period. In the third part, the optimized concentration of plant extract was used against a constant weight of glucose (3 g) and xylose (3 g), and subsequently the growth was observed for the same time period.…”

Antidiabetes and Antioxidant agents from Clausena excavata root as medicinal plant of Myanmar

“…One of the most frequent effects of uncontrolled diabetes is raised blood glucose. It could lead to fatal damages to the blood vessels, nerves, eyes, kidneys and eventually the heart [1,2]. Diabetes is not only lethal but it is also the major cause of blindness, heart attacks, kidney failure, strokes, gangrene, and neuropathy especially for adults [3].…”