Antidiabetic potential ofMusaspp. inflorescence: a systematic review

Abstract

Objectives Extracts of parts Musa spp. have been used for the treatment of various diseases in traditional medicine. Studies have shown that these extracts have hypoglycaemic properties. The aim of this work was to gather evidence on the antidiabetic effects of Musa spp. inflorescence. Methods A systematic review was conducted with searches in three electronic databases, along with manual searches. Studies evaluating the antidiabetic properties of extracts of flower or bract of the genus Musa (in vitro or in vivo) were included. Key findings Overall, 16 studies were found. The reported assays were of hypoglycaemic effects, oral glucose tolerance, inhibitory activities in carbohydrate metabolism and digestive enzymes, enhanced glucose uptake activity and popular use of the extract in patients with diabetes type 2. In vitro studies showed that use of the extract was associated with antidiabetic effects (e.g. increased glucose uptake and inhibition of carbohydrate digestion enzymes). In induced diabetic models, Musa spp. extracts showed dose‐dependent glycaemic level reductions compared with pharmacological drugs (P < 0.05). Summary In general, promising results regarding antidiabetic activity were found for inflorescence of Musa spp., suggesting that this plant could represent a natural alternative therapy for treating diabetes mellitus type 2.

Isolation of flavonoids from Musa acuminata Colla (Simili radjah, ABB) and the in vitro inhibitory effects of its leaf and fruit fractions on free radicals, acetylcholinesterase, 15‐lipoxygenase, and carbohydrate hydrolyzing enzymes

“…It has been reported in the literature that Musa species have antioxidant and antidiabetic potential, especially the inflorescence part, friut, and the flowers samples (Adedayo, Oboh, Oyeleye, & Olasehinde, 2016;Kalita et al, 2016). Vilhena et al (2018) found 16 studies reporting the antidiabetic property of the inflorescence (flowers and bract) of Musa spp., which all supported the ethnomedicinal claim that cooked flowers are able to treat diabetes mellitus. Some other extensive reviews have been compiled on the bioactive compounds from fruit, sap, and peel of banana (Pothavorn et al, 2010;Singh et al, 2016;Tsamo et al, 2015).…”

Antioxidant and anti-diabetic activities of crude ethanolic extract from the banana inflorescence of musa (ABB group) namwa maliong

“…diabetic activity of extracts from banana flowers or inflorescence toward the inhibition of -glucosidase and -amylase enzyme, inhibition of diabetes in animals, or stimulation of glucose uptake in muscle cells[6][7][8][9].Together, those findings illustrate the health benefits of banana flowers and inflorescence.Musa (ABB group) Namwa Mali-Ong is an edible banana that belongs to the ABB banana cultivar group. This cultivar is well-known throughout Thailand as Thai people utilize all parts of the tree.…”

“…The inflorescence of this banana is mainly used as a vegetable in many Thai dishes. Although many investigations have shown an anti-diabetic activity of banana inflorescence[6][7][8][9], the anti-diabetic activity of Musa (ABB group) Namwa Mali-Ong inflorescence has not been illustrated. Therefore, this study used an ethanolic extract of the entire inflorescence from Musa (ABB group) Namwa Mali-Ong to analyze its anti-diabetic activity.…”