Antidiabetic effects of protein hydrolysates from Trachinotus ovatus and identification and screening of peptides with α-amylase and DPP-IV inhibitory activities

Review: Enzymatic hydrolysates of fish by-products: technological advantages and bioactive properties

“…In model studies with streptozotocininduced diabetes in rats, golden pompano (Trachinotus ovatus) protein hydrolysates produced by hydrolysis with trypsin led to a reduction in the effects of polyphagia, insulin secretion, and glycemic levels, as well as a protective effect on kidney and liver tissues. The authors have also found 25 potential bioactive peptides, with small molecular weights, composed of 2 to 6 amino acids rich in Pro, Arg, Phe, and Asn, and a high concentration of hydrophobic peptides (WAN et al, 2023).…”

“…Trypsin,E/S 3000 U/g, ph 8.0, 37 ºC, 4 h golden pompano (Trachinotus ovatus)muscle (WAN et al, 2023).…”

Performance of Azolla pinnata fern protein hydrolysates as an emulsifier and nutraceutical ingredient in an O/W emulsion system and their effect on human gut microbiota and mammalian cells

“…2.6.5 α-Amylase inhibitory activity. The α-amylase inhibitory activity of all the emulsions was assessed as per the method of Wan et al 22 with some changes. Here, 20 µL of the emulsion sample was mixed with 10 µL of α-amylase (1 U per mL) in sodium phosphate buffer (20 mM, pH 6.9, containing 6 mM NaCl) and preincubated at 37 °C for 20 min.…”

Isolation and identification of an α-glucosidase inhibitory peptide from extruded soybean protein and its hypoglycemic activity in T2DM mice

“…Studies have demonstrated that low molecular weight hydrophobic peptides display higher α-glucosidase inhibitory activity and hypoglycemic activity. 12,44 Hydrophobic peptides can bind to bile salts to reduce cholesterol levels and facilitate their hypolipidemic ability. 45 In addition, some low molecular weight, hydrophobic peptides exhibit an antioxidant effect and high digestive stability.…”