Antidepressants in the treatment of agoraphobia and obsessive-compulsive disorder

Mavissakalian, Matig

doi:10.1016/0010-440x(83)90080-9

Cited by 10 publications

(1 citation statement)

References 39 publications

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“…Second-intention pharmacological approaches include trials of alternative medications as monotherapies with an Imipraminic or an α2 antagonist. Tricyclic antidepressants (TCA) cover both depression and certain anxiety disorders including GAD or PD, but are less commonly used due to tolerability issues [15–17]. Clomipramine appeared to be more effective than placebo in the treatment of Obsessive-compulsive disorders (OCD), and is recommended by the World Federation of Societies of Biological Psychiatry (WFSBP) and the American Psychiatric association (APA) in this indication [8, 9].…”

Section: Discussionmentioning

confidence: 99%

Clinical guidelines for the management of depression with specific comorbid psychiatric conditions French recommendations from experts (the French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental)

Bennabi¹,

Yrondi²,

Charpeaud³

et al. 2019

BMC Psychiatry

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BackgroundRecommendations for pharmacological treatments of major depression with specific comorbid psychiatric conditions are lacking.MethodThe French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental developed expert consensus guidelines for the management of depression based on the RAND/UCLA Appropriatneness Method. Recommendations for lines of treatment are provided by the scientific committee after data analysis and interpretation of the results of a survey of 36 psychiatrist experts in the field of major depression and its treatments.ResultsThe expert guidelines combine scientific evidence and expert clinician’s opinion to produce recommendations for major depression with comorbid anxiety disorders, personality disorders or substance use disorders and in geriatric depression.ConclusionThese guidelines provide direction addressing common clinical dilemmas that arise in the pharmacologic treatment of major depression with comorbid psychiatric conditions.

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Section: Discussionmentioning

confidence: 99%