Antidepressant discontinuation can be problematic for patients but relapse rates might be reduced with cognitive behavioural therapy or mindfulness-based cognitive therapy

Antidepressant Discontinuation Syndrome: A Common but Underappreciated Clinical Problem

“…In addition, cognitive behavioral therapy and mindfulnessbased therapies may be helpful in some patients. 26 Tapering regimens have not been validated in systematic studies; therefore, recommendations are based on anecdotal opinion as an art more than a science. 8 Research is needed to provide solid evidence-based recommendations.…”

EBN Perspectives, Mental Health

“…The issue of discontinuing antidepressants is a concern for many mental health practitioners as it may lead to unacceptable side effects and relapse of depression. A systematic review by Maund et al (2019)12 suggested that cognitive behavioural therapy (CBT) or mindfulness-based cognitive therapy may reduce relapse rates, although the meaningful analysis of the identified literature was hampered by the heterogeneity of studies. Future research needs to adopt more robust outcome measures and comparable, standardised longitudinal studies.…”