Anticoagulant antiplaquettaire passager et cellules de Hargraves au cours d’une ostéomyélosclérose

The Association between Autoimmunity and Agnogenic Myeloid Metaplasia

“…This disease preceded the overt manifestation of AMM by 3 years and was characterized by neuropathy, arthritis, scleroderma-like features, the presence of autoantibodies to peripheral nerve, acetylcholine receptor and nuclear antigens and by cryoglobulins. It seems that AMM is not infrequently accompanied or preceded by a Coombs' positive haemolytic anaemia (1,12,13), by a positive tests for rheumatoid factor and LE cells (14)(15)(16), by anti-organ antibodies (16), by circulating immune complexes (17) and by cryoglobulinaemia (12). In addition, a few patients with AMM associated with SLE or scleroderma have been described (18,19).…”