Anticellular PEO coatings on titanium surfaces by sequential electrospinning and crosslinking processes

Abstract

Titanium implants having some superior properties for tissue replacements have been widely used in biomedical fields. However, the implants are vulnerable to bacterial attacks and therefore they must be modified. In this study, two kinds of titanium surfaces, bare (Ti-b) and sandpapered (Ti-p) titanium, were used and electrospinning method was utilized for coating them with poly(ethylene oxide) (PEO) nanofibers with average diameter of 180 nm. In order to obtain insoluble coating, the PEO nanofibers were crosslinked by UV-initiating and crosslinking agent, pentaerythritol triacrylate (PETA), in the presence of UV irradiation at 366nm wavelength. Fibroblastic MC3T3-E1 preosteoblasts and S. epidermidis bacteria were cultured on these surfaces to investigate their attachment and proliferation behavior. The preosteoblasts cultured on Tip exhibited better initial adhesion than that of Ti-b at the end of the 4 h of incubation period, which reveals the importance of surface roughness. The bacteria adhered and colonized on Ti-b surfaces at the end of the 24 h of incubation. In contrast, Ti surfaces modified by the PEO nanofibers inhibited cellular and bacterial attachment significantly. This study discloses that electrospinning and subsequent crosslinking of PEO can be evaluated as an effective approach for creating anticellular coatings for Ti implants.

Structural, wear and thermal behaviour of Cu–Al2O3–graphite hybrid metal matrix composites

“…Moreover hardness of the samples showed a decreasing trend with addition of reinforcements due to the soft texture and lubricating property of graphite. [26][27][28] The samples with lower or no graphite content (pure copper) were hard and showed a brittle fracture whilst the samples with higher graphite content were less hard and yielded more thereby exhibiting higher compressive strength. Figure 6 shows continuous rise in compressive strength from lower wt% of reinforcements in CAG001 to higher wt% of reinforcements in CAG004.…”

“…19 The aforementioned attributes of the prepared material have been analysed in order to discern the abilities of the prepared material from the pure metal in achieving the desired properties. 20,[22][23][24][25][26][27][28][29][30][31][32][33] The aim of the present work is to study the effect of reinforcements content on phase, microstructure, density, hardness, wear, compressive strength and specific heat of the Cu-(Al 2 O 3 -C) composites. Copper matrix composites reinforced with Al 2 O 3 and graphite are widely used in structural and thermal applications.…”

“…19 The aforementioned attributes of the prepared material have been analysed in order to discern the abilities of the prepared material from the pure metal in achieving the desired properties. 20,22–33…”

Wear, optimization and surface analysis of Al-Al2O3-TiO2 hybrid metal matrix composites

“…The acetone was used for removing the loose debris from the surface of the specimen. 31–35 At low load, the wear is known as primary wear or abrasive wear. The SEM image of AlAlT01 (Al Matrix) showed deep groove as compared to the other specimen of hybrid composites represented in Figure 3.…”

Double-segregated multiwalled carbon nanotube/silicone composites with large electrical to thermal conductivity ratios via in-situ silicone emulsion polymerization

“…17 Currently, various functional composite coatings are being extensively investigated for various applications, such as anticellular coatings, porous scaffolds, and anticorrosion coatings. 18–20…”