Antibody-Mediated Immunity in the Presence of Mirex and DDT ,

Abstract

The objective of these experiments was to evaluate the influence of Mirex (dodecachlorooctahydro-l,3,3,-metheno 2Hcyclobuta (CD) pentaline) and DDT (

Influence of Temperature on the Immune Response of Birds

“…Among such factors are: microbial toxins (Pier and Heddleston, 1970;Pier et al, 1971;Michael et al, 1973;Thaxton et al, 1974a), hypoxia (Tengerdy, 1970), heavy metals (Thaxton and Parkhurst, 1973;Morgan et al, 1975), non-ionic radiation (McRee et al, 1977), pesticides (Glick and Whatley, 1966;Glick, 1972Glick, , 1974Latimer and Siegel, 1974;Subba Rao and Glick, 1977a), mechanical stress (Schmidt et al, 1976), social interactions Gross and Siegel, 1965;Gross and Colmano, 1967, 1969Siegel and Latimer, 1975), restraint (Thaxton and Briggs, 1972), and nutrients (Tengerdy and Heinzerling, 1972;Tengerdy, 1976;Tengerdy and Brown, 1977).…”

Alterations in T-lymphocyte sub-set profiles and cytokine secretion by PBMC of systemic lupus erythematosus patients uponin vitroexposure to organochlorine pesticides

“…They can stimulate, suppress, or deregulate the immune system, depending on concentration and duration of dose, toxicity/bioreactivity, total body load, and the nutritionat status of the individual. OCP that are known to alter the immune system are DDT, chlordane, aldrin, lindane, hexachlorobenzene, mirex, and arochlor (a polychloroorobiphenyl) (Glick, 1974;Street and Sharma, 1975;Giurgea et al, 1978;Silkworth and Loose, 1980). Direct T-lymphocyte triggering is found with many OCP.…”

Pesticide-Induced Immunotoxicity: Are Great Lakes Residents at Risk?

“…In contrast to the other priority pesticides found in the Great Lakes Basin, numerous studies have been conducted on the effect of DDT on the immune system of laboratory animals (39,(47)(48)(49)(50). In general, the immune system is not a sensitive target organ for toxicity.…”