Antibody-Gold Nanoparticle Bioconjugates for Biosensors: Synthesis, Characterization and Selected Applications

Zhang, Lu; Mazouzi, Yacine; Salmain, Michèle; Liedberg, Bo; Boujday, Souhir

doi:10.1016/j.bios.2020.112370

Cited by 157 publications

(114 citation statements)

References 149 publications

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“…In general, the synthesis of NPs is of great interest because of their unique properties that can be incorporated into composite fibers, biosensor materials, cryogenic super-conducting materials, cosmetic products, and electronic components [ 88 ]. However, due to climate change and the depletion of natural resources, the synthesis of AuNPs and AgNPs from plant extracts, and even more by agricultural wastes, is a major topic for encouraging sustainable development in agro-industrial labors.…”

Section: Aunps and Agnps Applications In Agriculturementioning

confidence: 99%

Green Synthesis of Gold and Silver Nanoparticles from Plant Extracts and Their Possible Applications as Antimicrobial Agents in the Agricultural Area

Henríquez¹,

et al. 2020

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Currently, metal nanoparticles have varied uses for different medical, pharmaceutical, and agricultural applications. Nanobiotechnology, combined with green chemistry, has great potential for the development of novel and necessary products that benefit human health, environment, and industries. Green chemistry has an important role due to its contribution to unconventional synthesis methods of gold and silver nanoparticles from plant extracts, which have exhibited antimicrobial potential, among other outstanding properties. Biodiversity-rich countries need to collect and convert knowledge from biological resources into processes, compounds, methods, and tools, which need to be achieved along with sustainable use and exploitation of biological diversity. Therefore, this paper describes the relevant reported green synthesis of gold and silver nanoparticles from plant extracts and their capacity as antimicrobial agents within the agricultural field for fighting against bacterial and fungal pathogens that can cause plant, waterborne, and foodborne diseases. Moreover, this work makes a brief review of nanoparticles’ contribution to water treatment and the development of “environmentally-friendly” nanofertilizers, nanopesticides, and nanoherbicides, as well as presenting the harmful effects of nanoparticles accumulation in plants and soils.

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Section: Aunps and Agnps Applications In Agriculturementioning

confidence: 99%

Green Synthesis of Gold and Silver Nanoparticles from Plant Extracts and Their Possible Applications as Antimicrobial Agents in the Agricultural Area

Henríquez¹,

et al. 2020

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“…IgGs are glycoproteins with a molecular weight of 150 kDa, a Y-shaped 3D structure, and an approximate size of 12 × 14 × 7 nm, comprising two antigen binding sites located at the two extremities of the F ab domains. Their association to spherical nanoparticles has been widely studied [ 196 ]. AuNR-antibody bioconjugates operate either in homogeneous solution-phase or in solid-phase when deposited on planar substrates as discussed in what follows.…”

Section: Applications Of Aunrs In Lspr Biosensingmentioning

confidence: 99%

Gold Nanorods for LSPR Biosensing: Synthesis, Coating by Silica, and Bioanalytical Applications

Pellas

Mazouzi

et al. 2020

Biosensors

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Nanoparticles made of coinage metals are well known to display unique optical properties stemming from the localized surface plasmon resonance (LSPR) phenomenon, allowing their use as transducers in various biosensing configurations. While most of the reports initially dealt with spherical gold nanoparticles owing to their ease of synthesis, the interest in gold nanorods (AuNR) as plasmonic biosensors is rising steadily. These anisotropic nanoparticles exhibit, on top of the LSPR band in the blue range common with spherical nanoparticles, a longitudinal LSPR band, in all respects superior, and in particular in terms of sensitivity to the surrounding media and LSPR-biosensing. However, AuNRs synthesis and their further functionalization are less straightforward and require thorough processing. In this paper, we intend to give an up-to-date overview of gold nanorods in LSPR biosensing, starting from a critical review of the recent findings on AuNR synthesis and the main challenges related to it. We further highlight the various strategies set up to coat AuNR with a silica shell of controlled thickness and porosity compatible with LSPR-biosensing. Then, we provide a survey of the methods employed to attach various bioreceptors to AuNR. Finally, the most representative examples of AuNR-based LSPR biosensors are reviewed with a focus put on their analytical performances.

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“…The other effect is the greatly enhanced local electric field, which is strongest at the surface and quickly reduces with distance. Due to the unusual properties of the metal nanostructures, they are widely used in optical detection [21], molecular imaging [22,23], biosensors [24,25], and other fields [26][27][28]. Plasmonic NPs are also introduced into lanthanide luminescent materials, and the luminescent properties of lanthanide materials can be finely modulated by the LSPR effect.…”

Section: Lspr Effectmentioning

confidence: 99%

Modulated Luminescence of Lanthanide Materials by Local Surface Plasmon Resonance Effect

et al. 2021

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Lanthanide materials have great applications in optical communication, biological fluorescence imaging, laser, and so on, due to their narrow emission bandwidths, large Stokes’ shifts, long emission lifetimes, and excellent photo-stability. However, the photon absorption cross-section of lanthanide ions is generally small, and the luminescence efficiency is relatively low. The effective improvement of the lanthanide-doped materials has been a challenge in the implementation of many applications. The local surface plasmon resonance (LSPR) effect of plasmonic nanoparticles (NPs) can improve the luminescence in different aspects: excitation enhancement induced by enhanced local field, emission enhancement induced by increased radiative decay, and quenching induced by increased non-radiative decay. In addition, plasmonic NPs can also regulate the energy transfer between two close lanthanide ions. In this review, the properties of the nanocomposite systems of lanthanide material and plasmonic NPs are presented, respectively. The mechanism of lanthanide materials regulated by plasmonic NPs and the scientific and technological discoveries of the luminescence technology are elaborated. Due to the large gap between the reported enhancement and the theoretical enhancement, some new strategies applied in lanthanide materials and related development in the plasmonic enhancing luminescence are presented.

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Antibody-Gold Nanoparticle Bioconjugates for Biosensors: Synthesis, Characterization and Selected Applications

Cited by 157 publications

References 149 publications

Green Synthesis of Gold and Silver Nanoparticles from Plant Extracts and Their Possible Applications as Antimicrobial Agents in the Agricultural Area

Green Synthesis of Gold and Silver Nanoparticles from Plant Extracts and Their Possible Applications as Antimicrobial Agents in the Agricultural Area

Gold Nanorods for LSPR Biosensing: Synthesis, Coating by Silica, and Bioanalytical Applications

Modulated Luminescence of Lanthanide Materials by Local Surface Plasmon Resonance Effect

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