2003
DOI: 10.1590/s0004-282x2003000500010
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Abstract: -One third of cases of cerebral ischemia have no clear etiology. A humoral response to the atherosclerotic plaques components beta2-glycoprotein I (beta2-gpI) and heat-shock proteins (Hsp) might be involved in the pathogenesis of stroke. This case-control study includes a complete profile of anti-beta2-gpI antibodies and testing of IgG antibodies to the 60/65 kilodaltons (kDa) Hsp in stroke patients. Ninety-three patients with acute ischemic stroke and 93 controls were evaluated for age, sex, race, hypertensio… Show more

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Cited by 40 publications
(36 citation statements)
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References 31 publications
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“…O papel de ambos anti-Hsp 60 e anti-Hsp 65 como fatores de risco para isquemia cerebral em fase aguda foi recentemente avaliado (65) .…”
Section: Anticorpos Anti-hsp E Doença Vascu-lar Cerebralunclassified
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“…O papel de ambos anti-Hsp 60 e anti-Hsp 65 como fatores de risco para isquemia cerebral em fase aguda foi recentemente avaliado (65) .…”
Section: Anticorpos Anti-hsp E Doença Vascu-lar Cerebralunclassified
“…Em relação aos anticorpos anti-Hsp 65, a freqüên-cia de teste positivo foi também maior em casos (34,4%) do que em controles (9,7%), com valor p de significância (p < 0,001). Após análise multivariada, a presença de IgG anti-Hsp 65 se comportou como fator de risco independente para infarto cerebral (OR 3,2) (65) .…”
Section: Anticorpos Anti-hsp E Doença Vascu-lar Cerebralunclassified
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